ZNF853 Inhibitors
The chemical class known as ZNF853 Inhibitors encompasses a variety of compounds that target indirect pathways or processes associated with ZNF853's activity. These inhibitors interact with epigenetic modifiers and signaling pathways that can, in turn, influence the function of ZNF853 within the cell. For example, chemicals like 5-Azacytidine and RG108, by inhibiting DNA methyltransferases, can change the methylation status of DNA, possibly altering the transcriptional control exerted by ZNF853. Histone deacetylase inhibitors such as Trichostatin A and SAHA can modify chromatin structure and gene expression profiles, which may affect the regulatory roles of ZNF853.
Simultaneously, compounds that modulate specific signaling pathways like CHIR99021 and ICG-001, which target GSK-3 and Wnt/β-catenin pathways respectively, could alter the transcriptional activity in which ZNF853 is potentially involved. Similarly, BIX-01294 and EPZ-6438, by inhibiting histone methyltransferases, may change the chromatin context of ZNF853's target genes. Agents like Olaparib and Nutlin-3, which affect DNA repair and p53 signaling respectively, might also influence ZNF853's activity if it is implicated in DNA damage response or p53-mediated transcription. Lastly, compounds such as JQ1 and Disulfiram may impact transcriptional regulation or protein stability, thereby influencing ZNF853's activity or levels indirectly.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that alters DNA methylation, potentially affecting ZNF853's role in gene regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that changes chromatin structure, potentially affecting ZNF853's access to DNA. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor that can alter gene expression, possibly impacting ZNF853-mediated transcription. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor that can change methylation patterns, potentially influencing ZNF853's genomic interactions. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
A GSK-3 inhibitor that can influence Wnt signaling, potentially affecting ZNF853-related transcriptional activity. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
A G9a histone methyltransferase inhibitor that can affect chromatin structure, potentially influencing ZNF853 function. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
An EZH2 inhibitor that can affect gene expression by altering histone methylation, potentially impacting ZNF853's regulatory roles. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
A PARP inhibitor affecting DNA repair pathways, which may influence ZNF853's role if connected to DNA damage responses. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
An MDM2 antagonist that stabilizes p53, potentially affecting ZNF853's activity if it is involved in p53-regulated gene expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
A BET bromodomain inhibitor that can alter transcription, potentially impacting ZNF853 if it interacts with bromodomain-containing proteins. | ||||||