ZNF827 Inhibitors
ZNF827 inhibitors are chemical compounds that modulate the activity of ZNF827, which stands for Zinc Finger Protein 827. ZNF827 is a transcription factor characterized by the presence of zinc finger domains, which are DNA-binding motifs. This protein is known for its involvement in the regulation of gene expression by binding to specific DNA sequences and modulating the transcription of target genes. ZNF827 has been implicated in various cellular processes, including cell cycle control, DNA repair, and chromatin organization.
ZNF827 inhibitors exert their effects by interfering with the DNA-binding capacity or transcriptional activity of ZNF827, disrupting its role in gene regulation. This interference can lead to alterations in the expression of downstream target genes, potentially influencing various cellular functions. Researchers employ ZNF827 inhibitors as invaluable tools to investigate the specific roles of ZNF827 in different cellular contexts and to gain a deeper understanding of the molecular mechanisms that underlie gene expression and transcriptional regulation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that inhibits DNA methyltransferases, potentially leading to demethylation and activation of some genes while repressing others, including possibly ZNF827. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
A histone deacetylase inhibitor which can alter chromatin structure and gene expression, potentially affecting ZNF827 transcription. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to GC-rich sequences in DNA, interfering with transcription factor binding and potentially downregulating ZNF827 expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Has been shown to inhibit the transcription of a number of genes, potentially including ZNF827, by an unknown mechanism. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-azacytidine, it inhibits DNA methyltransferases, potentially affecting the methylation status and expression of ZNF827. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Another histone deacetylase inhibitor which may change chromatin accessibility and influence ZNF827 expression. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Known to inhibit NF-κB pathway which may lead to altered expression of multiple genes including possibly ZNF827. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
A PARP inhibitor that can interfere with DNA repair and may incidentally affect the expression levels of various genes. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
A cyclin-dependent kinase inhibitor that may alter cell cycle progression and consequently affect gene expression profiles. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $450.00 $500.00 $1350.00 $10404.00 | 4 | |
A thiopeptide compound that has been shown to inhibit FoxM1, a transcription factor that may regulate genes such as ZNF827. | ||||||