ZNF75A Activators
Chemicals classified as ZNF75A activators encompass a diverse range of compounds that indirectly influence the activity of the ZNF75A protein through modulation of gene expression, chromatin accessibility, and metal ion homeostasis. These chemicals include inhibitors of DNA methyltransferases and histone deacetylases, which can alter the epigenetic landscape, enhancing the transcriptional activity of genes including those regulated by zinc finger proteins. Zinc supplementation, provided by compounds like ZnCl2, directly supports the structural and functional integrity of zinc finger domains, essential for the DNA-binding capability of proteins like ZNF75A.
Moreover, compounds that modulate signaling pathways and transcription factor activity, such as Resveratrol and Curcumin, can influence the cellular environment in a manner that promotes the expression and function of a broad array of proteins, including those within the zinc finger family. Similarly, epigenetic influencers like Epigallocatechin gallate (EGCG) and Trichostatin A, by affecting gene expression patterns, can create a cellular context conducive to the enhanced activity of ZNF75A. Additionally, agents that affect the cellular balance of metal ions, such as Disulfiram and D-Penicillamine, indirectly contribute to the regulation of metalloprotein activities, including the structural and functional modulation of zinc finger proteins.
This comprehensive approach, focusing on the indirect activation and support of ZNF75A protein functionality, highlights the intricate interplay between epigenetic regulation, metal ion homeostasis, and transcriptional control. Through the collective action of these compounds, the cellular and molecular conditions are tailored to foster an environment that supports the activity and regulatory roles of ZNF75A, emphasizing the broad and interconnected mechanisms through which the activity of zinc finger proteins can be influenced within the cellular milieu.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Inhibits DNA methyltransferases, increasing gene expression by promoting a more open chromatin structure. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor, enhancing gene expression by increasing histone acetylation and chromatin accessibility. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor, potentially enhancing the expression of genes by preventing DNA methylation. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Chelates copper, indirectly affecting the balance of metal ions critical for the function of metalloproteins, including zinc finger proteins. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Modulates various signaling pathways and could influence gene expression patterns relevant to zinc finger protein activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Affects transcription factor activity and signaling pathways, possibly influencing the expression and function of proteins like ZNF75A. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Influences epigenetic modifications and has been shown to affect gene expression, potentially impacting zinc finger protein activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, it increases chromatin accessibility and could enhance the expression of genes regulated by ZNF75A. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
Serves as a methyl donor in various biochemical processes including DNA methylation, indirectly influencing gene expression. | ||||||
Penicillamine | 52-67-5 | sc-205795 sc-205795A | 1 g 5 g | $45.00 $94.00 | ||
Can chelate metal ions, affecting the activity of metalloproteins and potentially influencing the function of zinc finger proteins. | ||||||