ZNF498 inhibitors belong to a specialized class of chemical compounds designed to target and modulate the activity of ZNF498, which stands for Zinc Finger Protein 498. ZNF498 is a transcription factor, and transcription factors are essential regulators of gene expression within cells, governing when and how specific genes are turned on or off. ZNF498, in particular, contains zinc finger domains, which are known for their DNA-binding properties, allowing them to interact with specific DNA sequences. This protein has been identified as a player in various cellular processes, including gene regulation, chromatin remodeling, and cellular response to environmental cues. Inhibitors of ZNF498 are developed to interact with this specific protein, influencing its DNA-binding abilities, its interactions with other transcriptional regulators, or its participation in cellular processes where it plays a role.
Structurally, ZNF498 inhibitors are designed to engage with specific regions or binding sites on the ZNF498 protein. This interaction may disrupt the normal functioning of ZNF498 as a transcription factor, leading to alterations in gene expression patterns and cellular responses. The mechanisms by which ZNF498 inhibitors exert their effects can vary, but their primary aim is to provide researchers with a valuable tool for investigating the roles of ZNF498 in various cellular contexts. By studying the biochemical and functional aspects of ZNF498 and its modulation by inhibitors, researchers can gain insights into the complex molecular mechanisms governing gene regulation, cellular responses to stimuli, and the broader field of molecular and cellular biology, ultimately contributing to a deeper understanding of fundamental biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound can inhibit DNA methyltransferases, potentially downregulating the expression of genes, including potentially "zinc finger and SCAN domain containing 25". | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
It's a histone deacetylase inhibitor that can affect gene expression by altering chromatin structure. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that might prevent degradation of regulatory proteins, indirectly affecting the expression of various genes. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interferes with the action of RNA polymerase, potentially downregulating gene expression. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Rho-associated protein kinase (ROCK) inhibitor, which can affect various cellular processes, including gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can affect downstream signaling and potentially gene expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that might interfere with signaling pathways, potentially affecting gene expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that can impact downstream signaling and potentially gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor affecting protein synthesis and potentially the expression of specific genes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor which can impact signaling pathways and potentially gene expression. | ||||||