ZNF498 Activators
The class of chemicals known as ZNF498 activators includes compounds that can indirectly influence the activity of ZNF498 by modulating cellular processes and signaling pathways related to transcription and gene expression. These activators primarily include histone deacetylase and DNA methyltransferase. Histone deacetylase, such as trichostatin A, suberoylanilide hydroxamic acid (SAHA), sodium butyrate, valproic acid, sodium phenylbutyrate, mocetinostat, panobinostat, vorinostat, romidepsin, entinostat, and belinostat, function by increasing histone acetylation, thereby promoting an open chromatin structure that is more conducive to transcription. This can indirectly enhance the transcriptional activity of ZNF498, which acts as a transcription factor.
5-Azacytidine, a DNA methyltransferase inhibitor, represents the other type of ZNF498 activator. This compound reduces DNA methylation, which can lead to a less condensed chromatin structure and enhanced transcription. This alteration in the DNA methylation landscape can indirectly enhance the transcriptional activity of ZNF498. Thus, the shared mechanism by which these chemicals can act as ZNF498 activators is by modifying the chromatin structure to a more open state, thereby facilitating the transcription of genes, including those controlled by ZNF498.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA is another histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium butyrate is a short-chain fatty acid that acts as a histone deacetylase inhibitor, indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $75.00 $163.00 $622.00 $4906.00 $32140.00 | 43 | |
Sodium phenylbutyrate is a histone deacetylase inhibitor and can indirectly promote transcriptional activity, potentially including that of ZNF498. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $210.00 $242.00 $1434.00 | 2 | |
Mocetinostat is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat is a histone deacetylase inhibitor, increasing histone acetylation and thus indirectly promoting transcriptional activity, potentially including that of ZNF498. | ||||||