Date published: 2026-5-16

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ZNF498 Inhibitors

ZNF498 inhibitors belong to a specialized class of chemical compounds designed to target and modulate the activity of ZNF498, which stands for Zinc Finger Protein 498. ZNF498 is a transcription factor, and transcription factors are essential regulators of gene expression within cells, governing when and how specific genes are turned on or off. ZNF498, in particular, contains zinc finger domains, which are known for their DNA-binding properties, allowing them to interact with specific DNA sequences. This protein has been identified as a player in various cellular processes, including gene regulation, chromatin remodeling, and cellular response to environmental cues. Inhibitors of ZNF498 are developed to interact with this specific protein, influencing its DNA-binding abilities, its interactions with other transcriptional regulators, or its participation in cellular processes where it plays a role.

Structurally, ZNF498 inhibitors are designed to engage with specific regions or binding sites on the ZNF498 protein. This interaction may disrupt the normal functioning of ZNF498 as a transcription factor, leading to alterations in gene expression patterns and cellular responses. The mechanisms by which ZNF498 inhibitors exert their effects can vary, but their primary aim is to provide researchers with a valuable tool for investigating the roles of ZNF498 in various cellular contexts. By studying the biochemical and functional aspects of ZNF498 and its modulation by inhibitors, researchers can gain insights into the complex molecular mechanisms governing gene regulation, cellular responses to stimuli, and the broader field of molecular and cellular biology, ultimately contributing to a deeper understanding of fundamental biological processes.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound can inhibit DNA methyltransferases, potentially downregulating the expression of genes, including potentially "zinc finger and SCAN domain containing 25".

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

It's a histone deacetylase inhibitor that can affect gene expression by altering chromatin structure.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Proteasome inhibitor that might prevent degradation of regulatory proteins, indirectly affecting the expression of various genes.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Interferes with the action of RNA polymerase, potentially downregulating gene expression.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Rho-associated protein kinase (ROCK) inhibitor, which can affect various cellular processes, including gene expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor that can affect downstream signaling and potentially gene expression.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor that might interfere with signaling pathways, potentially affecting gene expression.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor that can impact downstream signaling and potentially gene expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

mTOR inhibitor affecting protein synthesis and potentially the expression of specific genes.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

p38 MAPK inhibitor which can impact signaling pathways and potentially gene expression.