ZDHHC19 Activators
ZDHHC19 Activators constitute a specialized group of chemical compounds designed to modulate the activity of the ZDHHC19 gene. This gene, categorized as an open reading frame (ORF) within the human genome, encodes an enzyme known as DHHC19, which belongs to the DHHC family of palmitoyl transferases. The precise biological functions and cellular roles of DHHC19 are currently under investigation. Activators of ZDHHC19 have been developed to explore the potential involvement of this enzyme in cellular processes, such as protein palmitoylation, membrane targeting, or other fundamental biological functions. By influencing the activity or interactions of DHHC19, these compounds offer a valuable tool for investigating its cellular roles and contribute to a deeper understanding of gene function within the human genome.
The exploration of ZDHHC19 activators necessitates a multidisciplinary approach, encompassing principles from synthetic chemistry, molecular biology, and cell biology. Developing these compounds requires a fundamental understanding of the DHHC19 enzyme, including its structural features and potential interaction partners within the cellular context. The identification of molecules capable of specifically enhancing the activity or interactions of DHHC19 involves the systematic screening of chemical libraries to identify compounds that can bind to the enzyme or modulate its function. This research encompasses in vitro assays to assess changes in enzyme activity or interactions, as well as cellular studies to observe the effects of ZDHHC19 activation on broader physiological processes. Techniques such as mass spectrometry can be employed to analyze protein palmitoylation, while fluorescence microscopy aids in studying cellular localization. Functional assays are also conducted to evaluate cellular responses, ultimately contributing to the elucidation of the functional significance of DHHC19 and its potential role in various cellular processes. These comprehensive investigations provide valuable insights into gene function within the human genome, shedding light on the roles of DHHC19 in cellular physiology and molecular biology.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol found in green tea that may modulate gene expression through epigenetic changes and antioxidant effects. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A bioactive compound from turmeric that can affect gene expression by modulating transcription factors and signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Found in cruciferous vegetables, it may influence gene expression through the activation of Nrf2 and detoxification pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
This compound from red grapes is known to activate SIRT1 and may influence gene expression through epigenetic mechanisms. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid with antioxidant properties that might modulate gene expression through various signaling pathways. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A histone deacetylase inhibitor that can open chromatin structure and potentially enhance gene transcription. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
It may affect DNA replication and cell cycle progression, potentially leading to changes in gene expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
A methylxanthine that may alter gene expression by inhibiting phosphodiesterases and altering cAMP levels. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
A PPARγ agonist that can modulate the expression of genes involved in metabolism and cell differentiation. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
An inhibitor of DNA methyltransferases that could lead to DNA demethylation and activation of gene expression. | ||||||