UGT2B Activators
The chemical class of UGT2B Activators encompasses compounds that can indirectly influence the activity of UGT2B through their effects on liver function, metabolic enzyme regulation, and detoxification pathways. These compounds do not directly activate UGT2B enzymes; instead, they modulate physiological and metabolic conditions that could enhance UGT2B's functional role in glucuronidation.
Compounds such as Phenobarbital, Rifampicin, Oltipraz, and Sulforaphane are known to induce liver enzymes, including phase II detoxifying enzymes, potentially leading to increased UGT2B activity. Curcumin, Resveratrol, and Dexamethasone, through their varied effects on liver metabolism and enzyme expression, could also influence UGT2B's function. Additionally, natural compounds like St. John's Wort, Capsaicin, Indole-3-carbinol, Ellagic Acid, and Naringenin are known to modulate liver enzyme activity. Their influence on metabolic pathways could indirectly enhance the activity of UGT2B enzymes involved in drug metabolism and detoxification.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
An antibiotic known to induce liver enzymes, possibly enhancing UGT2B activity. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
A chemopreventive agent that can induce phase II detoxifying enzymes, including UGT2B. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Found in cruciferous vegetables, known to induce phase II detoxifying enzymes, potentially affecting UGT2B. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Exhibits properties that can influence liver enzyme regulation, possibly impacting UGT2B activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol that may influence liver function and enzyme activity, potentially affecting UGT2B. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A corticosteroid that can influence liver metabolism and enzyme expression, potentially impacting UGT2B. | ||||||
Hypericin | 548-04-9 | sc-3530 sc-3530A | 1 mg 5 mg | $66.00 $214.00 | 11 | |
Known to induce several liver enzymes, could potentially enhance UGT2B activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Found in chili peppers, known to influence metabolism and may affect liver enzyme function, including UGT2B. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Found in cruciferous vegetables, known to modulate phase I and II enzymes, potentially affecting UGT2B. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A polyphenol with potential effects on liver enzymes and metabolism, could influence UGT2B activity. | ||||||