THSD4 Inhibitors
THSD4 inhibitors represent a diverse group of chemicals targeting key cellular processes involved in cell adhesion, migration, and survival. Y-27632 and H-1152, as ROCK inhibitors, modulate cytoskeletal dynamics by altering actin organization, impacting THSD4-associated processes related to cell adhesion and migration. NSC23766, a Rac1-specific inhibitor, influences small GTPase signaling, impacting cellular protrusions and cytoskeletal dynamics, thus affecting THSD4-associated processes related to cell migration and invasion. Latrunculin A, an actin polymerization inhibitor, disrupts cytoskeletal dynamics, altering cellular protrusions and influencing THSD4-associated processes related to cell migration and adhesion. LY294002, SB431542, and ML141 target PI3K, TGF-β receptor, and Cdc42, respectively, influencing downstream signaling events and impacting THSD4-associated processes related to cell survival, adhesion, and migration.
Blebbistatin, a myosin II inhibitor, modulates actomyosin contractility, altering cytoskeletal dynamics and cellular contractility, impacting THSD4-associated processes related to cell migration and adhesion. PP2, a Src family kinase inhibitor, modulates tyrosine kinase signaling, affecting downstream events and impacting THSD4-associated processes related to cell adhesion and migration. Cytosporone B, a nuclear receptor antagonist, modulates transcriptional regulation, altering gene expression patterns and influencing THSD4-associated processes related to cell survival and migration. SB203580, a p38 MAPK inhibitor, modulates signaling cascades, impacting THSD4-associated processes related to cell adhesion and migration. Rapamycin, an mTOR inhibitor, influences mTOR-mediated pathways, affecting downstream events and impacting THSD4-associated processes related to cell survival and migration. This diverse set of inhibitors provides valuable tools for investigating the intricate regulatory networks involving THSD4, offering insights into its role in cellular processes critical for cancer progression and other pathological conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632, a Rho-associated protein kinase (ROCK) inhibitor, modulates cytoskeletal dynamics. Its impact on ROCK-mediated signaling indirectly influences THSD4 by altering actin cytoskeleton organization, thus impacting THSD4-associated processes related to cell adhesion and migration. | ||||||
H-1152 dihydrochloride | 451462-58-1 | sc-203592 sc-203592A | 1 mg 5 mg | $102.00 $357.00 | 7 | |
H-1152, a Rho kinase (ROCK) inhibitor, modulates cytoskeletal dynamics. Its impact on ROCK-mediated signaling indirectly influences THSD4 by altering actin cytoskeleton organization, thus impacting THSD4-associated processes related to cell adhesion and migration. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A, an actin polymerization inhibitor, disrupts cytoskeletal dynamics. Its influence on actin dynamics indirectly affects THSD4 by altering cellular protrusions and cytoskeletal organization, impacting THSD4-associated processes related to cell migration and adhesion. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a phosphoinositide 3-kinase (PI3K) inhibitor, modulates signaling cascades. Its impact on PI3K-mediated pathways indirectly influences THSD4 by altering downstream signaling events, impacting THSD4-associated processes related to cell survival and migration. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542, a transforming growth factor-beta (TGF-β) receptor inhibitor, modulates TGF-β signaling. Its influence on TGF-β-mediated pathways indirectly affects THSD4 by altering downstream signaling events, impacting THSD4-associated processes related to cell adhesion and migration. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
ML141, a Cdc42-specific inhibitor, modulates small GTPase signaling. Its impact on Cdc42-mediated pathways indirectly influences THSD4 by altering cellular protrusions and cytoskeletal dynamics, impacting THSD4-associated processes related to cell migration and invasion. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Blebbistatin, a myosin II inhibitor, modulates actomyosin contractility. Its influence on myosin II activity indirectly affects THSD4 by altering cytoskeletal dynamics and cellular contractility, impacting THSD4-associated processes related to cell migration and adhesion. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2, a Src family kinase inhibitor, modulates tyrosine kinase signaling. Its impact on Src-mediated pathways indirectly influences THSD4 by altering downstream signaling events, impacting THSD4-associated processes related to cell adhesion and migration. | ||||||
Cytosporone B | 321661-62-5 | sc-252653 | 5 mg | $143.00 | 7 | |
Cytosporone B, a nuclear receptor antagonist, modulates transcriptional regulation. Its influence on nuclear receptors indirectly affects THSD4 by altering gene expression patterns, impacting THSD4-associated processes related to cell survival and migration. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580, a p38 mitogen-activated protein kinase (MAPK) inhibitor, modulates signaling cascades. Its impact on p38 MAPK-mediated pathways indirectly influences THSD4 by altering downstream signaling events, impacting THSD4-associated processes related to cell adhesion and migration. | ||||||