TCEAL6 Activators
The development of TCEAL6 Activators would involve an intricate understanding of the protein's structure and function. Structural analyses could be conducted using advanced techniques like X-ray crystallography or cryo-electron microscopy to identify binding sites for activator molecules. The goal would be to find compounds that can bind to TCEAL6 in a way that promotes its activity, perhaps by facilitating its binding to DNA or associated transcription factors, or by inducing conformational changes that increase its stability and functional capacity.
Subsequent to the structural analysis, the activity of these compounds would be assessed through biochemical assays tailored to measure the effects of the activators on TCEAL6. These could include DNA-binding assays to observe how the activators affect the interaction between TCEAL6 and target gene promoters, or transcription assays to measure any resultant changes in the rate of transcription elongation. Additionally, it would be important to determine the specificity of these activators for TCEAL6 to avoid off-target effects that could confound the results. Through such detailed research and development, TCEAL6 Activators could be refined and optimized, contributing to a deeper knowledge of transcriptional regulation and the role of TCEAL family members in cellular processes.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that may cause demethylation of gene promoters, potentially increasing gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that could lead to a more accessible chromatin state and upregulation of certain genes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, potentially leading to activation of transcription factors and upregulation of gene expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates PKC which can modulate transcription factors and affect gene expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
An inhibitor of the TGF-β receptor, which might increase gene expression by affecting SMAD signaling. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
As a potent estrogen, it can modulate gene expression through estrogen receptor signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Affects gene expression by activating retinoic acid receptors, which can regulate transcription. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that may mimic the action of cAMP, leading to activation of PKA and CREB and subsequent gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
An HDAC inhibitor that may increase acetylation of histones, leading to a relaxed chromatin structure and potentially enhancing gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to GC-rich DNA sequences and may alter transcription of genes regulated by Sp1 transcription factor. | ||||||