TCEAL6 Inhibitors
TCEAL6 Inhibitors target various steps in the process of transcription and RNA processing, which could indirectly influence the function of TCEAL6. α-Amanitin and DRB target RNA polymerase II, directly affecting the transcription elongation process. Triptolide's inhibition of the TFIIH complex and Flavopiridol Hydrochloride's targeting of CDK9 also disrupt transcription elongation, influencing TCEAL6 function. Actinomycin D interferes with RNA synthesis, which could have an indirect effect on transcriptional processes involving TCEAL6. I-BET151 and JQ1 inhibit BET bromodomain proteins, impacting transcription regulation at the chromatin level.
Pladienolide B and KPT 330 affect RNA processing and nuclear export, respectively, offering insight into post-transcriptional regulation that could intersect with TCEAL6 function. Rocaglamide and Cordycepin target translation and RNA polyadenylation, processes linked to overall gene expression regulation. Lastly, Burixafor, as a CXCR4 antagonist, represents an approach to modulate cell signaling pathways, which could have downstream effects on transcription regulation relevant to TCEAL6. They provide avenues for exploring the transcriptional and post-transcriptional processes that may be related to its function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, impacting transcription elongation and potentially affecting TCEAL6-related processes. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Inhibits transcription by targeting the XPB subunit of TFIIH, which is involved in transcription elongation. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II transcription elongation. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $311.00 | ||
Inhibits CDK9, a component of the positive transcription elongation factor b (P-TEFb), affecting transcription elongation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Interferes with the elongation process of RNA synthesis by binding to DNA. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
Inhibits the BET family of bromodomain proteins, impacting transcription regulation. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Another BET bromodomain inhibitor, affecting transcriptional regulation. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $290.00 $5572.00 $10815.00 $25000.00 $65000.00 $2781.00 | 63 | |
Inhibits the spliceosome, potentially impacting RNA processing and transcription regulation. | ||||||
KPT 330 | 1393477-72-9 | sc-489062 | 5 mg | $170.00 | ||
Inhibits exportin 1 (XPO1), affecting nuclear export of RNA and potentially influencing transcription regulation. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Inhibits eukaryotic initiation factor 4A (eIF4A), affecting translation and possibly linked to transcriptional regulation. | ||||||