TAF II p130 Activators
TAF II p130 Activators encompass a spectrum of chemical compounds that indirectly stimulate the functional activity of TAF II p130 by targeting various chromatin and transcription regulation mechanisms. The activity of TAF II p130, pivotal in the assembly of the TFIID complex, is facilitated by histone deacetylase inhibitors such as Trichostatin A and SAHA. These compounds induce a relaxed chromatin state, improving TAF II p130 access to DNA and enhancing transcription initiation. Similarly, the DNA methyltransferase inhibitor 5-Azacytidine reduces methylation, promoting a transcription-friendly chromatin environment conducive to TAF II p130 function.
Anacardic Acid and Beta-Estradiol exert their effects via the modification of histone acetylation and chromatin remodeling, respectively, which can lead to improved recruitment and activity of TAF II p130. Retinoic Acid, through its receptor-mediated action, and S-Adenosylmethionine, by influencing methylation patterns, both create a genomic landscape that could bolster TAF II p130's role in transcriptional activation.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that leads to a more relaxed chromatin structure, potentially enhancing the binding of TFIID complex components like TAF II p130 to DNA, thereby promoting transcriptional activation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that reduces DNA methylation, which can increase the accessibility of transcription factors including TAF II p130 to promoters for transcriptional activation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor that relaxes chromatin to facilitate the assembly of transcription factors and coactivators including TAF II p130 onto the DNA, enhancing transcription. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
A histone acetyltransferase activator that can lead to hyperacetylation of histones, increasing transcription factor access to DNA, potentially benefiting the function of TAF II p130 in transcription initiation. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
A pre-mRNA splicing inhibitor that may indirectly enhance the role of TAF II p130 in transcription initiation by affecting the mRNA processing and maturation stages. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
A hormone that can modulate chromatin structure through estrogen receptor-mediated recruitment of coactivators and chromatin modifiers, which could facilitate TAF II p130 function in transcription. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A molecule that influences gene transcription via the retinoic acid receptor, which may enhance the recruitment of the TFIID complex including TAF II p130 to target genes. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
A donor of methyl groups that can influence DNA and histone methylation, potentially creating a landscape conducive for TAF II p130 to function in transcriptional activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid and histone deacetylase inhibitor that leads to chromatin relaxation, possibly aiding TAF II p130's role in transcription initiation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound that can modulate various signaling pathways and potentially influence chromatin remodeling, thus affecting TAF II p130's involvement in transcription. | ||||||