Sox-6 Activators
Sox6 Activators is a class of compounds that may indirectly influence the activity of Sox6, a transcription factor with a key role in embryonic development and cell fate determination. These compounds do not directly activate Sox6 but modulate the cellular pathways Sox6 is involved in. Retinoic acid, a modulator of transcriptional activity, and dexamethasone, a corticosteroid, affect the regulation of Sox6 involved in cell differentiation and response to glucocorticoids, respectively.
Forskolin and IBMX, both acting on the cAMP pathway, can modulate transcriptional regulators like Sox6. Sodium butyrate and Trichostatin A, as histone deacetylase inhibitors, and 5-Azacytidine, a DNA methyltransferase inhibitor, modify chromatin and DNA structures, influencing Sox6 expression. PD98059, LY294002, SB431542, Rapamycin, and Y-27632 are inhibitors of different pathways – MAPK/ERK, PI3K/Akt, TGF-beta, mTOR, and Rho/ROCK, respectively. By modulating these pathways, they can influence Sox6 expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid modulates transcriptional activity. It can influence the regulation of Sox6, which plays a role in cell differentiation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a corticosteroid that can influence the glucocorticoid response elements in the promoters of target genes, potentially affecting Sox6 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin acts on cAMP pathway, which may modulate the activity of Sox6, a transcriptional regulator. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX inhibits phosphodiesterase, increasing cAMP levels and potentially influencing transcription factors like Sox6. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor that can modify chromatin structure, potentially influencing Sox6 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is another histone deacetylase inhibitor that can modify chromatin structure, potentially influencing Sox6 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor that can modify DNA methylation patterns, potentially influencing Sox6 expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that can modulate the MAPK/ERK pathway, potentially affecting Sox6 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can modulate the PI3K/Akt pathway, potentially affecting Sox6 expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542 is a TGF-beta receptor inhibitor that can modulate the TGF-beta pathway, potentially affecting Sox6 expression. | ||||||