Sox-6 inhibitors belong to a specific chemical class of compounds designed to modulate the activity of the Sox-6 transcription factor. Sox-6 is a member of the Sox (SRY-related HMG box) family of transcription factors, which play essential roles in the regulation of gene expression during various cellular processes. These inhibitors are designed to specifically target Sox-6 and interfere with its function, thereby affecting downstream gene expression pathways. By selectively inhibiting the activity of Sox-6, these compounds may have the potential to alter cellular responses and physiological processes associated with Sox-6 dysregulation.
The mechanism of action of Sox-6 inhibitors typically involves direct interaction with Sox-6 or its co-regulators, influencing the binding of Sox-6 to its target genes or interfering with its transcriptional activation function. Research into Sox-6 inhibitors is ongoing, with scientists exploring the structural characteristics and molecular interactions necessary to develop potent and selective compounds. Understanding the specific roles of Sox-6 in different cellular contexts and its involvement in disease processes may provide valuable insights for potential future applications of these inhibitors in various fields of research.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Celastrol, Celastrus scandens | 34157-83-0 | sc-202534 | 10 mg | $155.00 | 6 | |
Celastrol is known for its anti-inflammatory and antioxidant properties. It has been studied for its potential to impede Sox-6 and its role in conditions related to Sox-6 dysregulation. | ||||||
Ro 31-8220 | 138489-18-6 | sc-200619 sc-200619A | 1 mg 5 mg | $90.00 $240.00 | 17 | |
This is a chemical compound belonging to the family of bisindolylmaleimides. It has shown inhibitory effects on various protein kinases, including Sox-6. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542 is a selective inhibitor of transforming growth factor-beta (TGF-beta) type I receptor (ALK5), which is implicated in Sox-6 regulation. | ||||||
Dorsomorphin dihydrochloride | 1219168-18-9 | sc-361173 sc-361173A | 10 mg 50 mg | $182.00 $736.00 | 28 | |
Also known as Compound C, dorsomorphin is an AMP-activated protein kinase (AMPK) inhibitor that has been shown to inhibit Sox-6 expression indirectly through the TGF-beta pathway. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $75.00 $150.00 $215.00 $650.00 $1224.00 $4296.00 $7818.00 | 8 | |
Repsox is another TGF-beta type I receptor (ALK5) inhibitor that has demonstrated the ability to regulate Sox-6 expression. | ||||||
Hesperadin | 422513-13-1 | sc-490384 | 10 mg | $304.00 | ||
Hesperadin is an inhibitor of Aurora B kinase, and it has been reported to modulate Sox-6 expression in certain cellular contexts. | ||||||
Lys05 | 1391426-24-6 | sc-507532 | 5 mg | $140.00 | ||
Lys05 is a lysosome-targeting agent that has been investigated for its potential to inhibit Sox-6 in certain pathological conditions. | ||||||
SRPIN 340 | 218156-96-8 | sc-394310 | 10 mg | $222.00 | 1 | |
SRPIN340 is a serine/arginine-rich protein kinase (SRPK) inhibitor, and it has been associated with the regulation of Sox-6 splicing. |