Sox-17 Inhibitors
Sox-17 inhibitors belong to a specific class of chemical compounds designed to target and inhibit the activity of the transcription factor known as Sox-17. Sox-17, short for SRY (sex-determining region Y)-box 17, is a member of the Sox (SRY-related HMG box) family of transcription factors, which play critical roles in regulating gene expression and controlling various cellular processes. Specifically, Sox-17 is involved in the regulation of embryonic development, cell differentiation, and maintenance of tissue homeostasis. It is particularly crucial in the development of various organs, including the endoderm-derived organs such as the pancreas, liver, and gut.
Sox-17 inhibitors are designed to interfere with the normal function of Sox-17 by binding to it or disrupting its interactions with other molecules within the cell. This inhibition can lead to downstream effects on gene expression patterns, ultimately influencing cellular processes controlled by Sox-17. Researchers have been exploring Sox-17 inhibitors as tools to better understand the molecular mechanisms underlying embryonic development and tissue regeneration. By studying the consequences of Sox-17 inhibition, scientists aim to uncover insights into cellular differentiation and harnesses this knowledge for various applications. These inhibitors have the ability to be valuable research tools in the field of developmental biology, shedding light on the intricate processes governing tissue formation and regeneration in multicellular organisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a cytidine analog that can be incorporated into DNA and RNA, leading to demethylation of DNA. The demethylation can alter gene expression patterns, potentially downregulating Sox-17. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor, which can lead to changes in chromatin structure and gene expression. It may alter the expression of genes, including Sox-17, by modifying histone acetylation levels. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine is a nucleoside analog that can cause DNA hypomethylation. By altering methylation patterns, it has the potential to modulate the expression of various genes, possibly including Sox-17. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is an isoflavone found in soy, and it has been shown to have effects on gene expression and epigenetic modifications. It may potentially modulate Sox-17 expression through these mechanisms. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Suberoylanilide Hydroxamic Acid is a histone deacetylase inhibitor, which can alter chromatin structure and gene expression. It has the potential to modulate Sox-17 expression through changes in histone acetylation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a natural compound found in turmeric, known for its anti-inflammatory and antioxidant properties. It can also modulate gene expression and may potentially impact Sox-17 levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound found in grapes and red wine, known for its potential health benefits. It can influence gene expression and epigenetic modifications, possibly affecting Sox-17. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Fluorouracil is a pyrimidine analog that can be incorporated into RNA and DNA, leading to perturbations in nucleic acid metabolism and gene expression. It may have an impact on Sox-17 expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane is a compound found in cruciferous vegetables, known for its potential anticancer properties. It can modulate gene expression and epigenetic modifications, potentially influencing Sox-17. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid found in many plants, known for its antioxidant properties. It can modulate various signaling pathways and gene expression, possibly impacting Sox-17 expression. | ||||||