SmcY Activators
The class of SmcY (KDM5D) activators comprises a range of compounds primarily influencing epigenetic regulation and chromatin remodeling, potentially modulating the activity of KDM5D, a key histone demethylase. This group includes DNA methyltransferase inhibitors like 5-Azacytidine and histone deacetylase inhibitors such as Trichostatin A and Sodium Butyrate. These compounds can lead to changes in chromatin structure, enhancing transcriptional activity and potentially upregulating KDM5D's role in epigenetic regulation.
Compounds like Retinoic Acid and Vitamin D3, known for their roles in modulating gene expression, are included for their potential impact on transcriptional processes that could influence KDM5D activity. Resveratrol, with its effects on metabolic pathways, and Curcumin, known for its broad effects on cellular signaling, could modulate KDM5D activity in processes related to aging, metabolism, and inflammation. Forskolin, by increasing cAMP levels, and antioxidants like Quercetin and Epigallocatechin Gallate (EGCG), might indirectly impact KDM5D activity by modulating transcription regulation and cellular stress response pathways. Additionally, compounds like Sulforaphane, known for influencing gene expression and cellular detoxification pathways, and Niacin, due to its role in cellular metabolism, are included for their potential indirect influence on KDM5D activity through metabolic pathways.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially affecting chromatin structure and gene expression, thereby influencing KDM5D activity in epigenetic regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
An HDAC inhibitor, could alter chromatin structure and enhance transcription, potentially upregulating KDM5D activity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Another HDAC inhibitor, possibly affecting chromatin remodeling and influencing KDM5D activity in gene regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression; could modulate KDM5D activity by affecting pathways involved in cellular differentiation and chromatin remodeling. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Modulates gene expression; may influence KDM5D activity in chromatin remodeling and gene regulation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences sirtuin activity; may modulate KDM5D activity in pathways related to aging and metabolic regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects various signaling pathways; could influence KDM5D activity by altering transcription regulation and chromatin structure. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, potentially affecting transcription regulation and KDM5D activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with antioxidant properties; may modulate KDM5D activity through pathways related to oxidative stress and inflammation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences metabolic and inflammatory pathways; could indirectly modulate KDM5D activity. | ||||||