Date published: 2025-10-22

1-800-457-3801

SCBT Portrait Logo
Seach Input

SmcY Inhibitors

Chemical inhibitors termed "SmcY inhibitors," in a broad sense, would encompass a variety of chemical classes, each designed to interact with specific domains or active sites within a protein or to interrupt protein-protein interactions relevant to the activity of "SmcY". These inhibitors would generally be characterized by their ability to bind to the target protein with high specificity and affinity, thereby modulating its function.

The inhibitors listed encompass a range of biochemical mechanisms such as kinase inhibition, proteasome inhibition, and signaling pathway interference. They often mimic the structure of natural substrates or competitive molecules and can either block the active site or alter the conformation of the protein to prevent its normal function. This action on signaling pathways illustrates a method by which cellular processes are modulated at a molecular level, affecting the function of "SmcY" indirectly through upstream or downstream effects within a given pathway. The molecules cited include both reversible and irreversible inhibitors, small molecules, and more complex structures, all of which can profoundly impact the biological activity of target proteins within the implicated pathways.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent kinase inhibitor affecting a wide range of kinases, which could inhibit "SmcY" activity if it phosphorylates or is activated by phosphorylation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K inhibitor that would inhibit the PI3K-Akt signaling pathway. If "SmcY" is downstream of PI3K or Akt, this inhibition can decrease its activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits mTOR, a key protein in cell growth and metabolism signaling pathways. If "SmcY" is regulated by mTOR, rapamycin can suppress its activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 is a p38 MAPK inhibitor. Inhibition of p38 MAPK can affect "SmcY" if it is a part of or is regulated by the p38 MAPK signaling pathway.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is a JNK inhibitor. If "SmcY" is involved in the JNK signaling pathway, its activity would be affected by this compound.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 is an inhibitor of MEK, which would affect "SmcY" if it is part of the MAPK/ERK pathway or if its activity is modulated by this pathway.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Bortezomib inhibits the proteasome, potentially decreasing the degradation of inhibitory proteins that control "SmcY" activity or increasing the degradation of "SmcY" itself if it is a substrate.

ZM 336372

208260-29-1sc-202857
1 mg
$46.00
2
(1)

ZM336372 is a specific inhibitor of Raf-1 kinase. If "SmcY" activity is dependent on the Raf/MEK/ERK signaling pathway, this compound can decrease its activity.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin is a potent inhibitor of PI3K. Inhibition of PI3K would lead to decreased activity of "SmcY" if it is regulated by or involved in the PI3K signaling pathway.

Imatinib mesylate

220127-57-1sc-202180
sc-202180A
25 mg
100 mg
$44.00
$109.00
61
(1)

Imatinib is a tyrosine kinase inhibitor, primarily targeting BCR-ABL, c-Kit, and PDGF receptors. If "SmcY" is a tyrosine kinase or is regulated by tyrosine kinase signaling, imatinib could inhibit its function.