Date published: 2025-11-22

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Smad3 Antibodies

Santa Cruz Biotechnology features a diverse variety of Smad3 monoclonal antibodies for advanced research in cellular signaling pathways. Smad3 Antibodies are compatible with western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smad3 is a critical mediator in the transforming growth factor-beta (TGF-β) signaling pathway, playing a vital role in regulating gene expression, cell proliferation, and differentiation. Smad3 functions are essential in various biological processes, including embryogenesis, tissue homeostasis, and immune responses. Dysregulation of Smad3 has been implicated in numerous diseases, including cancer and fibrosis, highlighting its importance as a target for therapeutic intervention. Researchers can explore specific protein interactions and cellular localization patterns through multiple detection methods, enabling comprehensive analysis of Smad3 activity. Understanding Smad3's role in different cellular contexts can provide valuable insights into disease mechanisms and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of cellular signaling pathways and disease mechanisms.

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Smad3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Smad1/2/3 Antibody (H-2)

sc-7960mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h and mink
78
(7)

Smad2/3 Antibody (C-8)

sc-133098mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
125
(42)

Smad2/3 Antibody (E-1)

sc-376928mouse IgG1 κ2-29 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(5)

Smad2/3 Antibody (A-3)

sc-398844mouse IgG2b κ145-164 (h)WB, IP, IF, IHC(P), ELISAm, r, h
16
(13)

Smad3 Antibody (38-Q)

sc-101154mouse IgG2a κ120-222 (h)WB, IP, IF, IHC(P), ELISAm, r, h
128
(13)

Smad3 Antibody (4C9)

sc-517574mouse IgG(h)IF, IHC(P)m, r, h
1
(0)

Phospho-Specific Smad3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Smad3 Antibody (1D9)

sc-517575mouse IgGSer 425 (h)IF, IHC(P)m, r, h
32
(2)

Smad3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad3 CRISPR/Cas9 KO Plasmid (h2)

sc-400069-KO-2hGene KnockoutGFP
2
(0)

Smad3 Double Nickase Plasmid (h)

sc-400069-NIChGene KnockoutPuromycin
2
(0)

Smad3 Double Nickase Plasmid (h2)

sc-400069-NIC-2hGene KnockoutPuromycin
2
(0)

Smad3 CRISPR/Cas9 KO Plasmid (m)

sc-421526mGene KnockoutGFP0
(0)

Smad3 HDR Plasmid (m)

sc-421526-HDRmHomology Directed RepairPuromycin0
(0)

Smad3 Double Nickase Plasmid (m)

sc-421526-NICmGene KnockoutPuromycin0
(0)

Smad3 Double Nickase Plasmid (m2)

sc-421526-NIC-2mGene KnockoutPuromycin0
(0)

Smad3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad3 CRISPR Activation Plasmid (h)

sc-400069-ACThGene ActivationPuro, Blast, Hygro
2
(0)

Smad3 CRISPR Activation Plasmid (h2)

sc-400069-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

Smad3 Lentiviral Activation Particles (h)

sc-400069-LAChGene ActivationPuro, Blast, Hygro
2
(0)

Smad3 Lentiviral Activation Particles (h2)

sc-400069-LAC-2hGene ActivationPuro, Blast, Hygro
2
(0)

Smad3 CRISPR Activation Plasmid (m)

sc-421526-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Smad3 CRISPR Activation Plasmid (m2)

sc-421526-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad3 Lentiviral Activation Particles (m)

sc-421526-LACmGene ActivationPuro, Blast, Hygro0
(0)

Smad3 Lentiviral Activation Particles (m2)

sc-421526-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad3 siRNA (h)

sc-38376hGene SilencingN/A
40
(0)

Smad3 shRNA Plasmid (h)

sc-38376-SHhGene SilencingPuromycin
40
(0)

Smad3 shRNA (h) Lentiviral Particles

sc-38376-VhGene SilencingPuromycin
40
(0)

Smad3 siRNA (m)

sc-38377mGene SilencingN/A
7
(0)

Smad3 shRNA Plasmid (m)

sc-38377-SHmGene SilencingPuromycin
7
(0)

Smad3 shRNA (m) Lentiviral Particles

sc-38377-VmGene SilencingPuromycin
7
(0)

Smad3 siRNA (r)

sc-77326rGene SilencingN/A
5
(0)

Smad3 shRNA Plasmid (r)

sc-77326-SHrGene SilencingPuromycin
5
(0)

Smad3 shRNA (r) Lentiviral Particles

sc-77326-VrGene SilencingPuromycin
5
(0)

Smad2/3 siRNA (h)

sc-37238hGene SilencingN/A
38
(0)

Smad2/3 shRNA Plasmid (h)

sc-37238-SHhGene SilencingPuromycin
38
(0)

Smad2/3 shRNA (h) Lentiviral Particles

sc-37238-VhGene SilencingPuromycin
38
(0)

Smad2/3 siRNA (m)

sc-37239mGene SilencingN/A
18
(0)

Smad2/3 shRNA Plasmid (m)

sc-37239-SHmGene SilencingPuromycin
18
(0)

Smad2/3 shRNA (m) Lentiviral Particles

sc-37239-VmGene SilencingPuromycin
18
(0)