Date published: 2026-5-4

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Smad7 Antibodies

Santa Cruz Biotechnology features a diverse variety of Smad7 monoclonal antibodies for research in understanding cellular signaling pathways. Smad7 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smad7 is a critical regulator of the TGF-beta signaling pathway, acting as an antagonist to prevent excessive signaling that can lead to fibrosis and other pathological conditions. By modulating the activity of Smad proteins, Smad7 plays a vital role in maintaining cellular homeostasis and influencing processes such as cell proliferation, differentiation, and apoptosis. Understanding Smad7 function is essential for elucidating its implications in various diseases, including cancer and autoimmune disorders. Smad7 research has revealed significant roles in tissue repair, immune response regulation, and embryonic development. Investigating Smad7 expression patterns helps researchers understand its involvement in normal physiological processes and disease states. Current studies focus on how Smad7 regulation might be targeted for therapeutic interventions. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of Smad7's role in health and disease.

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Smad7 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Smad7 Antibody (B-8)

sc-365846mouse IgG1 κ319-397 (h)WB, IP, IF, ELISAm, r, h
87
(19)

Smad7 Antibody (Z8-B)

sc-101152mouse IgG2a κ160-261 (h)WB, IP, IF, IHC(P), ELISAm, r, h
30
(8)

Smad7 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad7 Double Nickase Plasmid (h)

sc-400251-NIChGene KnockoutPuromycin
1
(0)

Smad7 Double Nickase Plasmid (h2)

sc-400251-NIC-2hGene KnockoutPuromycin
1
(0)

Smad7 CRISPR/Cas9 KO Plasmid (m)

sc-421530mGene KnockoutGFP0
(0)

Smad7 HDR Plasmid (m)

sc-421530-HDRmHomology Directed RepairPuromycin0
(0)

Smad7 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad7 CRISPR/Cas9 KO Plasmid (h2)

sc-400251-KO-2hGene KnockoutGFP
1
(0)

Smad7 HDR Plasmid (h2)

sc-400251-HDR-2hHomology Directed RepairPuromycin
1
(0)

Smad7 CRISPR Activation Plasmid (h)

sc-400251-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Smad7 CRISPR Activation Plasmid (h2)

sc-400251-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Smad7 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad7 siRNA (h)

sc-36508hGene SilencingN/A
12
(0)

Smad7 shRNA Plasmid (h)

sc-36508-SHhGene SilencingPuromycin
12
(0)

Smad7 shRNA (h) Lentiviral Particles

sc-36508-VhGene SilencingPuromycin
12
(0)

Smad7 siRNA (m)

sc-36509mGene SilencingN/A
9
(0)

Smad7 shRNA Plasmid (m)

sc-36509-SHmGene SilencingPuromycin
9
(0)

Smad7 shRNA (m) Lentiviral Particles

sc-36509-VmGene SilencingPuromycin
9
(0)