Date published: 2025-11-22

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Smad5 Antibodies

Santa Cruz Biotechnology delivers a wide array of Smad5 monoclonal antibodies for advanced research in cellular signaling pathways. Smad5 monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Smad5 is a critical component of the TGF-beta signaling pathway, playing a vital role in regulating cell growth, differentiation, and apoptosis. Its function is essential for maintaining cellular homeostasis and responding to extracellular signals, making it a key player in developmental processes and tissue homeostasis. Dysregulation of Smad5 has been implicated in various diseases, including cancer, highlighting the significance of understanding its molecular mechanisms. Researchers can explore the complex interactions between Smad5 and other signaling molecules using specific detection methods. The high-quality Smad5 monoclonal antibodies enable precise investigation of TGF-beta signaling pathways in both normal and pathological conditions. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of cellular signaling and disease mechanisms.

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Smad5 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Smad5 Antibody (YY-6)

sc-101151mouse IgG2a κ105-182 (h)WB, IP, IF, ELISAm, r, h
6
(6)

Smad5 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad5 CRISPR/Cas9 KO Plasmid (h)

sc-400443hGene KnockoutGFP0
(0)

Smad5 HDR Plasmid (h)

sc-400443-HDRhHomology Directed RepairPuromycin0
(0)

Smad5 Double Nickase Plasmid (h)

sc-400443-NIChGene KnockoutPuromycin0
(0)

Smad5 Double Nickase Plasmid (h2)

sc-400443-NIC-2hGene KnockoutPuromycin0
(0)

Smad5 CRISPR/Cas9 KO Plasmid (m)

sc-421528mGene KnockoutGFP0
(0)

Smad5 HDR Plasmid (m)

sc-421528-HDRmHomology Directed RepairPuromycin0
(0)

Smad5 Double Nickase Plasmid (m)

sc-421528-NICmGene KnockoutPuromycin0
(0)

Smad5 Double Nickase Plasmid (m2)

sc-421528-NIC-2mGene KnockoutPuromycin0
(0)

Smad5 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad5 CRISPR Activation Plasmid (h)

sc-400443-ACThGene ActivationPuro, Blast, Hygro0
(0)

Smad5 CRISPR Activation Plasmid (h2)

sc-400443-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Smad5 Lentiviral Activation Particles (h)

sc-400443-LAChGene ActivationPuro, Blast, Hygro0
(0)

Smad5 Lentiviral Activation Particles (h2)

sc-400443-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Smad5 CRISPR Activation Plasmid (m)

sc-421528-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Smad5 CRISPR Activation Plasmid (m2)

sc-421528-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad5 Lentiviral Activation Particles (m)

sc-421528-LACmGene ActivationPuro, Blast, Hygro0
(0)

Smad5 Lentiviral Activation Particles (m2)

sc-421528-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Smad5 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Smad5 siRNA (h)

sc-38378hGene SilencingN/A
7
(0)

Smad5 shRNA Plasmid (h)

sc-38378-SHhGene SilencingPuromycin
7
(0)

Smad5 shRNA (h) Lentiviral Particles

sc-38378-VhGene SilencingPuromycin
7
(0)

Smad5 siRNA (m)

sc-38379mGene SilencingN/A
1
(0)

Smad5 shRNA Plasmid (m)

sc-38379-SHmGene SilencingPuromycin
1
(0)

Smad5 shRNA (m) Lentiviral Particles

sc-38379-VmGene SilencingPuromycin
1
(0)

Smad5 siRNA (r)

sc-63290rGene SilencingN/A
1
(0)

Smad5 shRNA Plasmid (r)

sc-63290-SHrGene SilencingPuromycin
1
(0)

Smad5 shRNA (r) Lentiviral Particles

sc-63290-VrGene SilencingPuromycin
1
(0)