SLC17A2 inhibitors are a class of chemical compounds that specifically target and inhibit the function of the SLC17A2 protein, a member of the solute carrier family. SLC17A2 is part of the larger SLC17 family, which is known for its role in transporting organic anions, including neurotransmitters and other small molecules, across cellular membranes. The inhibition of SLC17A2 can disrupt the transport processes it mediates, offering researchers a powerful tool to study the protein's function and its broader impact on cellular activities. By selectively inhibiting SLC17A2, scientists can explore how this transporter influences the distribution and concentration of specific anions within cells, and how these changes affect cellular metabolism and signaling.
The use of SLC17A2 inhibitors in research is particularly valuable for dissecting the role of this transporter in various biological systems. By blocking SLC17A2 activity, researchers can observe the resulting alterations in cellular processes, such as changes in ion gradients, neurotransmitter release, and intracellular signaling pathways. These studies help to elucidate the specific substrates transported by SLC17A2 and the physiological contexts in which this transporter is most active. Additionally, SLC17A2 inhibitors can be used to explore the regulatory mechanisms that control the expression and activity of this protein, providing insights into how cells maintain homeostasis in response to environmental and intracellular cues. Through these investigations, SLC17A2 inhibitors contribute to a deeper understanding of membrane transport mechanisms and the complex interplay between transport proteins and cellular function.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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D(−)-2-Amino-5-phosphonovaleric acid (D-AP5) | 79055-68-8 | sc-200434 | 5 mg | $95.00 | 2 | |
作为NMDA受体拮抗剂,AP5可间接影响谷氨酸信号和释放。 | ||||||
6-Cyano-7-nitroquinoxaline-2,3-dione | 115066-14-3 | sc-505104 | 10 mg | $204.00 | 2 | |
CNQX是一种强效AMPA受体拮抗剂,可间接影响谷氨酸信号和释放。 | ||||||
Kynurenic acid | 492-27-3 | sc-202683 sc-202683A sc-202683B | 250 mg 1 g 5 g | $25.00 $56.00 $135.00 | 6 | |
这是一种广谱兴奋性氨基酸受体拮抗剂,可减少谷氨酸信号。 | ||||||
Riluzole | 1744-22-5 | sc-201081 sc-201081A sc-201081B sc-201081C | 20 mg 100 mg 1 g 25 g | $20.00 $189.00 $209.00 $311.00 | 1 | |
利鲁唑抑制谷氨酸释放,间接影响SLC17A7的功能。 | ||||||
Ethosuximide | 77-67-8 | sc-211431 | 1 g | $300.00 | ||
这种化合物可降低T型钙通道活性,从而间接影响谷氨酸释放。 | ||||||
Lamotrigine | 84057-84-1 | sc-201079 sc-201079A | 10 mg 50 mg | $118.00 $476.00 | 1 | |
拉莫三嗪抑制电压敏感钠通道,导致谷氨酸释放减少。 | ||||||
Topiramate | 97240-79-4 | sc-204350 sc-204350A | 10 mg 50 mg | $105.00 $362.00 | ||
它调节GABA诱发的电流,间接影响谷氨酸释放。 | ||||||
Felbamate | 25451-15-4 | sc-203579 sc-203579A | 10 mg 50 mg | $101.00 $373.00 | ||
非氨酯是一种NMDA受体拮抗剂,间接影响谷氨酸信号和释放。 | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
一种质子载体,破坏质子梯度,可能影响SLC17A的功能。 | ||||||
Niflumic acid | 4394-00-7 | sc-204820 | 5 g | $31.00 | 3 | |
一种非甾体类抗炎药,可能间接影响离子通道和转运蛋白(如SLC17A)。 |