SETMAR Inhibitors
SETMAR, also known as SET Nuclear Proto-Oncogene and Transposase MARiner 1, is a bifunctional enzyme that possesses both histone methyltransferase (HMT) and DNA transposase activities. This unique dual functionality allows SETMAR to participate in various cellular processes, including chromatin remodeling, DNA repair, and genome stability. SETMAR inhibitors interact with the active sites or binding domains of this enzyme, thereby disrupting its normal functions and potentially impacting critical cellular processes dependent on SETMAR activity.
By inhibiting SETMAR, these compounds have the potential to interfere with its HMT and DNA transposase activities, which can result in alterations to chromatin structure and genome stability. The study of SETMAR inhibitors is of significant interest to researchers as it provides insights into the regulatory mechanisms governing these essential cellular functions. This knowledge contributes to our understanding of basic cell biology and may have implications in various research areas, such as epigenetics, DNA repair mechanisms, and genome integrity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for its impact on various signaling pathways, it could potentially affect the transcription factors regulating SETMAR. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
As a phytoalexin, it might influence gene expression patterns, potentially impacting SETMAR expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Known to affect multiple signaling pathways, it might have an indirect effect on SETMAR expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
As an isothiocyanate, it can influence epigenetic regulation and potentially affect SETMAR expression. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Known to inhibit various enzymes, it might indirectly affect pathways involved in SETMAR expression. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Impacts several cellular signaling pathways, which could potentially influence the expression of SETMAR. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A major component of green tea, known to affect various signaling molecules, potentially impacting SETMAR expression. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Has been shown to affect a wide range of cellular processes, which might indirectly influence SETMAR expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
As a phytoestrogen, it can modulate signaling pathways and potentially affect SETMAR expression. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Found in cruciferous vegetables, it can influence gene expression and may affect SETMAR expression. | ||||||