Date published: 2025-10-20

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Rock Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Rock Antibodies, specifically targeting the Rho-associated protein kinase (ROCK) family. Rock Antibodies are effective tools in various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ROCK proteins regulate cytoskeletal dynamics, cell migration, and cell adhesion, making them essential for various cellular processes, including smooth muscle contraction and neuronal function. The involvement of ROCK proteins in signaling pathways connects them to significant physiological and pathological conditions, such as cancer progression and cardiovascular diseases. Recent studies have highlighted the importance of ROCK proteins in embryonic development and tissue regeneration. Ongoing research continues to uncover new functions of ROCK proteins in cellular homeostasis and disease progression. Understanding ROCK protein regulation provides insights into potential therapeutic strategies for various medical conditions. Rock monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific knowledge and contribute to breakthrough discoveries in cell biology and disease treatment.

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Rock Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

cleaved Rock-1 Antibody (4H247)

sc-71965mouse IgG κ1113/1114 (h)WB, IPm, r, h and canine
2
(2)

cleaved Rock-1 Antibody (154C1465)

sc-52953mouse IgG1113/1114 (h)WB, IPm, r, h and canine
5
(4)

Rock-1 Antibody (G-6)

sc-17794mouse IgG1 κ755-840 (h)WB, IP, IF, IHC(P), ELISAm, r, h
92
(31)

Rock-1 Antibody (H-11)

sc-365628mouse IgG1 κ1327-1354 (h)WB, IP, IF, ELISAm, r, h
9
(2)

Rock-1 Antibody (B-1)

sc-374388mouse IgG2a κ1309-1346 (h)WB, IP, IF, ELISAm, r, h
9
(5)

Rock-2 Antibody (D-11)

sc-398519mouse IgG2a κ775-860 (h)WB, IP, IF, ELISAm, r, h
42
(14)

Rock-2 Antibody (30-J)

sc-100425mouse IgG2b κ1279-1389 (h)WB, IP, IF, ELISAm, r, h
7
(3)

Rock-2 Antibody (D-2)

sc-365275mouse IgG2b κ1353-1379 (r)WB, IP, IF, ELISAm, r, h
2
(3)

Rock CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rock-1 CRISPR/Cas9 KO Plasmid (h)

sc-400367hGene KnockoutGFP0
(0)

Rock-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400367-KO-2hGene KnockoutGFP0
(0)

Rock-1 HDR Plasmid (h2)

sc-400367-HDR-2hHomology Directed RepairPuromycin0
(0)

Rock-1 Double Nickase Plasmid (h)

sc-400367-NIChGene KnockoutPuromycin0
(0)

Rock-1 Double Nickase Plasmid (h2)

sc-400367-NIC-2hGene KnockoutPuromycin0
(0)

Rock-1 CRISPR/Cas9 KO Plasmid (m)

sc-422694mGene KnockoutGFP0
(0)

Rock-1 HDR Plasmid (m)

sc-422694-HDRmHomology Directed RepairPuromycin0
(0)

Rock-1 Double Nickase Plasmid (m)

sc-422694-NICmGene KnockoutPuromycin0
(0)

Rock-1 Double Nickase Plasmid (m2)

sc-422694-NIC-2mGene KnockoutPuromycin0
(0)

Rock-2 CRISPR/Cas9 KO Plasmid (h)

sc-400468hGene KnockoutGFP0
(0)

Rock-2 HDR Plasmid (h)

sc-400468-HDRhHomology Directed RepairPuromycin0
(0)

Rock-2 Double Nickase Plasmid (h)

sc-400468-NIChGene KnockoutPuromycin0
(0)

Rock-2 Double Nickase Plasmid (h2)

sc-400468-NIC-2hGene KnockoutPuromycin0
(0)

Rock-2 CRISPR/Cas9 KO Plasmid (m2)

sc-422695-KO-2m2Gene KnockoutGFP0
(0)

Rock-2 HDR Plasmid (m2)

sc-422695-HDR-2mHomology Directed RepairPuromycin0
(0)

Rock-2 Double Nickase Plasmid (m)

sc-422695-NICmGene KnockoutPuromycin0
(0)

Rock-2 Double Nickase Plasmid (m2)

sc-422695-NIC-2mGene KnockoutPuromycin0
(0)

Rock-2 CRISPR/Cas9 KO Plasmid (r)

sc-437370rGene KnockoutGFP0
(0)

Rock-2 HDR Plasmid (r)

sc-437370-HDRrHomology Directed RepairPuromycin0
(0)

Rock-2 Double Nickase Plasmid (r)

sc-437370-NICrGene KnockoutPuromycin0
(0)

Rock-2 Double Nickase Plasmid (r2)

sc-437370-NIC-2rGene KnockoutPuromycin0
(0)

Rock CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rock-1 CRISPR Activation Plasmid (h)

sc-400367-ACThGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 CRISPR Activation Plasmid (h2)

sc-400367-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 Lentiviral Activation Particles (h)

sc-400367-LAChGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 Lentiviral Activation Particles (h2)

sc-400367-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 CRISPR Activation Plasmid (m)

sc-422694-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 CRISPR Activation Plasmid (m2)

sc-422694-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 Lentiviral Activation Particles (m)

sc-422694-LACmGene ActivationPuro, Blast, Hygro0
(0)

Rock-1 Lentiviral Activation Particles (m2)

sc-422694-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (h)

sc-400468-ACThGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (h2)

sc-400468-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (h)

sc-400468-LAChGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (h2)

sc-400468-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (m)

sc-422695-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (m2)

sc-422695-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (m)

sc-422695-LACmGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (m2)

sc-422695-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (r)

sc-437370-ACTrGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 CRISPR Activation Plasmid (r2)

sc-437370-ACT-2rGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (r)

sc-437370-LACrGene ActivationPuro, Blast, Hygro0
(0)

Rock-2 Lentiviral Activation Particles (r2)

sc-437370-LAC-2rGene ActivationPuro, Blast, Hygro0
(0)

Rock siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rock-1 siRNA (h)

sc-29473hGene SilencingN/A
25
(0)

Rock-1 siRNA (h2)

sc-76025h2Gene SilencingN/A
1
(0)

Rock-1 shRNA Plasmid (h)

sc-29473-SHhGene SilencingPuromycin
25
(0)

Rock-1 shRNA Plasmid (h2)

sc-76025-SHh2Gene SilencingPuromycin
1
(0)

Rock-1 shRNA (h) Lentiviral Particles

sc-29473-VhGene SilencingPuromycin
25
(0)

Rock-1 shRNA (h2) Lentiviral Particles

sc-76025-Vh2Gene SilencingPuromycin
1
(0)

Rock-1 siRNA (m)

sc-36432mGene SilencingN/A
14
(0)

Rock-1 shRNA Plasmid (m)

sc-36432-SHmGene SilencingPuromycin
14
(0)

Rock-1 shRNA (m) Lentiviral Particles

sc-36432-VmGene SilencingPuromycin
14
(0)

Rock-1 siRNA (r)

sc-72179rGene SilencingN/A
1
(0)

Rock-1 shRNA Plasmid (r)

sc-72179-SHrGene SilencingPuromycin
1
(0)

Rock-1 shRNA (r) Lentiviral Particles

sc-72179-VrGene SilencingPuromycin
1
(0)

Rock-1 siRNA (bovine)

sc-270203bovineGene SilencingN/A0
(0)

Rock-1 shRNA Plasmid (bovine)

sc-270203-SHbovineGene SilencingPuromycin0
(0)

Rock-1 shRNA (bovine) Lentiviral Particles

sc-270203-VbovineGene SilencingPuromycin0
(0)

Rock-2 siRNA (h)

sc-29474hGene SilencingN/A
25
(0)

Rock-2 shRNA Plasmid (h)

sc-29474-SHhGene SilencingPuromycin
25
(0)

Rock-2 shRNA (h) Lentiviral Particles

sc-29474-VhGene SilencingPuromycin
25
(0)

Rock-2 siRNA (m)

sc-36433mGene SilencingN/A
7
(0)

Rock-2 shRNA Plasmid (m)

sc-36433-SHmGene SilencingPuromycin
7
(0)

Rock-2 shRNA (m) Lentiviral Particles

sc-36433-VmGene SilencingPuromycin
7
(0)

Rock-2 siRNA (r)

sc-108088rGene SilencingN/A
2
(0)

Rock-2 shRNA Plasmid (r)

sc-108088-SHrGene SilencingPuromycin
2
(0)

Rock-2 shRNA (r) Lentiviral Particles

sc-108088-VrGene SilencingPuromycin
2
(0)