Rock-2 Antibody (D-2): sc-365275
- Rock-2 Antibody (D-2) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1353-1379 at the C-terminus of Rock-2 of rat origin
- recommended for detection of Rock-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and bovine
- See Rock-2 (D-11): sc-398519 for Rock-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Rock-2 Antibody (D-2) for WB applications. This reagent is now offered in a bundle with Rock-2 Antibody (D-2) (see ordering information below).
Rock-2 Antibody (D-2) is a mouse monoclonal IgG2b antibody that detects Rock-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rock-2, also known as Rho-associated coiled-coil containing protein kinase 2, plays a crucial role in regulating various cellular processes, including cell migration, proliferation, and apoptosis, by acting as a downstream effector of the Rho GTPase signaling pathway. Rock-2 (D-2) antibody helps researchers study Rock-2′s ability to modulate the actin cytoskeleton, which is essential for maintaining cell shape and facilitating movement. Rock-2 is involved in the phosphorylation of myosin light chain, a key step in muscle contraction and cellular tension generation. Understanding Rock-2 function is vital, as dysregulation has been implicated in various diseases, including cancer and cardiovascular disorders. Anti-Rock-2 antibody (D-2) provides a reliable tool for researchers aiming to explore Rock-2′s intricate roles in cellular dynamics and potential as a therapeutic target.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rock-2 Antibody (D-2) | sc-365275 | 200 µg/ml | $316.00 | |||
Rock-2 Antibody (D-2): m-IgG2b BP-HRP Bundle | sc-548551 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rock-2 (D-2) Neutralizing Peptide | sc-365275 P | 100 µg/0.5 ml | $68.00 |