RhD inhibitors belong to a specific class of chemical compounds that have gained prominence in the field of immunology and blood group antigen research. The RhD antigen, also known as the Rhesus D antigen, is a blood group antigen found on the surface of red blood cells. It plays a significant role in blood transfusion compatibility and hemolytic disease of the newborn, a condition where maternal antibodies target fetal red blood cells. The term RhD inhibitors refers to a group of molecules meticulously designed to selectively target and modulate the expression or activity of the RhD antigen. These inhibitors serve as vital tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with RhD antigens.
RhD inhibitors typically function by interfering with the expression or function of RhD antigens on the surface of red blood cells. This interference can impact various aspects of blood compatibility and the immune response, particularly in the context of blood transfusions and maternal-fetal interactions. Researchers employ RhD inhibitors to gain insights into the physiological roles and molecular interactions of RhD antigens, aiming to advance our understanding of the fundamental mechanisms involved in blood group compatibility and immune responses related to the RhD antigen. Through the study of RhD inhibitors, scientists seek to unravel the complexities of blood group antigen systems, immune tolerance, and the broader field of immunohematology, contributing to our knowledge of how the immune system recognizes and interacts with blood group antigens.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor, potentially altering gene expression patterns by affecting DNA methylation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylases, affecting chromatin structure and gene expression, potentially influencing protein synthesis. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-Azacytidine, decitabine inhibits DNA methylation, potentially affecting the expression of various genes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
As an HDAC inhibitor, vorinostat modifies chromatin structure and can influence gene expression, potentially affecting protein synthesis. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor, affecting gene expression through epigenetic modifications. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin binds to DNA and affects gene transcription, potentially influencing the expression of various proteins. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin is an HDAC inhibitor that affects chromatin remodeling and gene expression, potentially impacting protein synthesis. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid, primarily used as an anticonvulsant, also has HDAC inhibitory activity, potentially affecting gene expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a selective HDAC inhibitor, affecting chromatin structure and potentially influencing gene expression. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat inhibits HDAC, affecting gene expression by modifying chromatin structure. |