RBP2 Activators
The chemical class termed RBP2 Activators encompasses a range of compounds that indirectly influence the activity of Retinoblastoma binding protein 2 (RBP2). These chemicals operate through various mechanisms, affecting different cellular signaling pathways and transcriptional regulation processes, which in turn can alter the functional state of RBP2.
One of the primary mechanisms through which these chemicals exert influence is by modulating chromatin structure and gene expression. Histone deacetylase inhibitors like Trichostatin A, SAHA, and Sodium Butyrate change chromatin accessibility, thereby potentially impacting the transcriptional regulatory roles of RBP2. DNA methylation patterns, crucial for gene expression and chromatin structure, are also targeted by compounds such as 5-Aza-2'-deoxycytidine, which can indirectly affect RBP2's role in transcriptional regulation. Furthermore, compounds like Vitamin C and Genistein impact DNA demethylation and tyrosine kinase signaling pathways, respectively, creating cascades of cellular events that can influence RBP2's regulatory roles. Similarly, the actions of Sulforaphane, Curcumin, LY294002, PD98059, and Rapamycin demonstrate the diverse spectrum of cellular processes that can be modulated to influence RBP2 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor. It alters chromatin structure and gene expression, potentially affecting RBP2's activity by changing the transcriptional landscape in which RBP2 operates. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
This compound is a DNA methyltransferase inhibitor, altering DNA methylation patterns. This can indirectly impact RBP2's role in chromatin remodeling and transcriptional regulation. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Vitamin C enhances the activity of TET enzymes, which are involved in DNA demethylation. This can influence the transcriptional regulation activities of RBP2 by altering epigenetic marks. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a phytoestrogen, acts as a tyrosine kinase inhibitor. This can affect signaling pathways that indirectly modulate RBP2's activity in transcription regulation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA is another histone deacetylase inhibitor, impacting chromatin structure and gene expression. This can indirectly influence RBP2's functional role in gene regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, Sodium Butyrate affects chromatin accessibility and gene expression, potentially impacting RBP2's regulatory roles. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol modulates sirtuin activity, particularly SIRT1, influencing chromatin remodeling and gene expression, which can indirectly affect RBP2's role in transcriptional regulation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane influences the Nrf2 pathway, involved in the cellular response to oxidative stress, potentially affecting RBP2's regulatory roles. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects the PI3K/Akt pathway, crucial for cell survival and proliferation, potentially influencing RBP2's activity in gene regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, which can modulate transcription factors and cofactors interacting with RBP2. | ||||||