Rad21 Inhibitors
The class of Rad21 inhibitors comprises a diverse array of compounds that target various cellular processes and pathways associated with Rad21 modulation. One example, CCG-203971, functions as a DNA-PK inhibitor, influencing Rad21 indirectly by disrupting DNA repair processes. This disruption extends to impacting downstream signaling pathways connected to Rad21 regulation, resulting in the dysregulation of Rad21-mediated cellular functions. The intricate relationship between CCG-203971 and Rad21 highlights the complexity of cellular processes involved in Rad21 modulation. Another inhibitor, NSC 617145, operates as an HDAC inhibitor, indirectly modulating Rad21 through epigenetic regulation. This compound influences chromatin structure and gene expression patterns associated with Rad21 function. The alteration in chromatin dynamics induced by NSC 617145 can impact Rad21's ability to participate in key cellular processes. Similarly, MLN4924, an NEDD8-activating enzyme (NAE) inhibitor, affects Rad21 indirectly by inhibiting the neddylation process. This inhibition impacts protein degradation pathways associated with Rad21 turnover, contributing to the intricate regulatory landscape governing Rad21 function.
These inhibitors, among others in the class, serve as valuable tools for unraveling the complex regulatory mechanisms governing Rad21 function. Their diverse modes of action underscore the multifaceted nature of Rad21 modulation, offering avenues for interventions targeting this protein. The insights gained from studying these inhibitors not only deepen our understanding of Rad21 biology but also provide a foundation for the development of novel strategies to modulate Rad21 in various cellular contexts.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CCG 203971 | 1443437-74-8 | sc-507360 | 10 mg | $89.00 | ||
DNA-PK inhibitor, potentially influences Rad21 indirectly by disrupting DNA repair processes and impacting downstream signaling pathways connected to Rad21 regulation. | ||||||
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $286.00 | 1 | |
NEDD8-activating enzyme (NAE) inhibitor, potentially affects Rad21 indirectly by inhibiting the neddylation process and impacting protein degradation pathways associated with Rad21 turnover. | ||||||
AZD7762 | 860352-01-8 | sc-364423 | 2 mg | $107.00 | ||
CHK1 inhibitor, indirectly influences Rad21 through disruption of the cell cycle checkpoint, affecting DNA repair and cellular processes associated with Rad21 function. | ||||||
THZ1 | 1604810-83-4 | sc-507542 | 1 mg | $95.00 | ||
CDK7 inhibitor, potentially modulates Rad21 indirectly by inhibiting transcriptional processes and impacting gene expression profiles associated with Rad21 regulation. | ||||||
BAY 87-2243 | 1227158-85-1 | sc-507483 | 5 mg | $100.00 | ||
CA9 inhibitor, indirectly influences Rad21 by impacting carbonic anhydrase IX (CA9)-mediated processes, potentially affecting cellular pathways linked to Rad21 function. | ||||||
Leflunomide | 75706-12-6 | sc-202209 sc-202209A | 10 mg 50 mg | $20.00 $83.00 | 5 | |
DHODH inhibitor, indirectly modulates Rad21 by disrupting pyrimidine biosynthesis and impacting cellular processes associated with Rad21 function. | ||||||
ETP-46464 | 1345675-02-6 | sc-497432 | 10 mg | $550.00 | ||
PLK1 inhibitor, potentially affects Rad21 indirectly by disrupting the mitotic processes regulated by Polo-like kinase 1 (PLK1), impacting pathways associated with Rad21 during cell division. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 inhibitor, potentially influences Rad21 indirectly by impacting glycogen synthase kinase-3 (GSK-3)-mediated processes, affecting cellular pathways linked to Rad21 function. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET inhibitor, indirectly modulates Rad21 through disruption of bromodomain and extraterminal (BET) protein-mediated processes, impacting gene expression profiles associated with Rad21 regulation. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $98.00 | ||
Bromodomain inhibitor, potentially affects Rad21 indirectly by disrupting bromodomain-mediated processes, impacting chromatin structure and gene expression patterns associated with Rad21 function. | ||||||