Molecular structure of PFI-1, CAS Number: 1403764-72-6
PFI-1 (CAS 1403764-72-6)
Alternate Names:
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinazolin-6-yl)-bezenesulfonamide; PF-06405761
Application:
PFI-1 is An epigenetic chemical probe.
CAS Number:
1403764-72-6
Molecular Weight:
347.39
Molecular Formula:
C16H17N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PFI-1 is an epigenetic chemical probe and a selective BET bromodomain inhibitor with activity at BRD2 (IC50 = 98 nM) and BRD4 (IC50 = 220 nM).
Inhibitor of:
2900008C10Rik, 4933408B17Rik, ACSL, ANKRD24, BRD1, BRD2, BRD4, BRD8, BRPF3, BSX, CA150, cbp146, CHD2, CHD9, D2Bwg1423e, Erg, Histone H2BM, HP1, LIN-53, Monomethyl Histone H4, N-CoR, NUT, OTTMUSG00000016788, PATZ1, Rad21, SCML2, Sp9, TGIF2, TM6SF2, TRIM12, TSPYL4, TSPYL6, ZFP383, ZMYND17, ZNF430, ZNF645, ZNF648, ZNF764, and ZSCAN4B.Activator of:
BAZ2B, BC032203, BRDT, BRP44, Brpf1, BRWD3, C11orf41_D430041D05Rik, CARD 11, GMF-β, hnRNP H′/hnRNP H2, IFI-27, LEUTX, MacroH2A1, Morc1, MPc3_CBX8, MSL-1, NELF-E, SVIP, TAF9A, TRAP100, ZBTB38, ZNF222, and ZSCAN18.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PFI-1, 5 mg | sc-478504 | 5 mg | $96.00 |