Date published: 2025-9-23

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PAK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PAK Antibodies for investigating p21-activated kinases (PAKs) in various cellular processes. PAK Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).PAKs are serine/threonine kinases that regulate cell morphology, motility, and survival. PAKs participate in signaling pathways that mediate responses to growth factors and stress, making them significant targets in cancer research and other diseases. Understanding PAK function can reveal new therapeutic opportunities for various medical conditions. Research has shown that PAKs influence cytoskeletal dynamics and cell adhesion. PAK signaling networks are essential for normal cellular development and tissue maintenance. Recent studies have highlighted PAK involvement in neurological disorders and immune system regulation. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of PAK biology and contribute to the development of targeted therapies.

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PAK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

α/β/γPAK Antibody (D-8)

sc-166174mouse IgG1 κ263-345 (m)WB, IP, IF, IHC(P), ELISAm, r, h
6
(8)

αPAK Antibody (A-6)

sc-166887mouse IgG1 κ246-470 (h)WB, IP, IF, ELISAm, r, h
14
(10)

γPAK Antibody (E-9)

sc-373740mouse IgG2b κ497-522 (h)WB, IP, IF, ELISAm, r, h
6
(9)

γPAK Antibody (F-12)

sc-133113mouse IgG1 κ2-41 (h)WB, IP, IF, ELISAm, r, h
1
(2)

γPAK Antibody (G-10)

sc-137208mouse IgG1 κ2-41 (h)WB, IP, IF, ELISAm, r, h

new

(2)

γPAK Antibody (H-4)

sc-377194mouse IgG2a κ7-43 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PAK4 Antibody (B-3)

sc-390507mouse IgG1 κ167-209 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(8)

PAK4 Antibody (B-6)

sc-393367mouse IgG1 κ101-240 (h)WB, IP, IF, ELISAm, r, h
5
(1)

PAK4 Antibody (6C1)

sc-81532mouse IgG1(h)WB, IPm, r, h and canine
1
(2)

PAK6 Antibody (H-6)

sc-393075mouse IgG2b κ71-370 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

PAK6 Antibody (C-2)

sc-393102mouse IgG2a κ71-370 (h)WB, IP, IF, ELISAh
1
(2)

Phospho-Specific PAK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-αPAK Antibody (17.Thr 423)

sc-135755mouse IgG2b κThr 423 (h)WB, ELISAm, r, h
4
(6)

p-PAK4 Antibody (93.Ser 474)

sc-135775mouse IgG2a κSer 474 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

PAK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

αPAK CRISPR/Cas9 KO Plasmid (h2)

sc-400857-KO-2hGene KnockoutGFP
1
(0)

αPAK HDR Plasmid (h2)

sc-400857-HDR-2hHomology Directed RepairPuromycin
1
(0)

αPAK Double Nickase Plasmid (h)

sc-400857-NIChGene KnockoutPuromycin
1
(0)

αPAK Double Nickase Plasmid (h2)

sc-400857-NIC-2hGene KnockoutPuromycin
1
(0)

αPAK Double Nickase Plasmid (m)

sc-422107-NICmGene KnockoutPuromycin0
(0)

αPAK Double Nickase Plasmid (m2)

sc-422107-NIC-2mGene KnockoutPuromycin0
(0)

βPAK CRISPR/Cas9 KO Plasmid (h)

sc-401109hGene KnockoutGFP0
(0)

βPAK HDR Plasmid (h)

sc-401109-HDRhHomology Directed RepairPuromycin0
(0)

βPAK Double Nickase Plasmid (h)

sc-401109-NIChGene KnockoutPuromycin0
(0)

βPAK Double Nickase Plasmid (h2)

sc-401109-NIC-2hGene KnockoutPuromycin0
(0)

βPAK CRISPR/Cas9 KO Plasmid (m)

sc-422108mGene KnockoutGFP0
(0)

βPAK Double Nickase Plasmid (m)

sc-422108-NICmGene KnockoutPuromycin0
(0)

βPAK Double Nickase Plasmid (m2)

sc-422108-NIC-2mGene KnockoutPuromycin0
(0)

γPAK CRISPR/Cas9 KO Plasmid (h)

sc-401595hGene KnockoutGFP0
(0)

γPAK HDR Plasmid (h)

sc-401595-HDRhHomology Directed RepairPuromycin0
(0)

γPAK Double Nickase Plasmid (h)

sc-401595-NIChGene KnockoutPuromycin0
(0)

γPAK Double Nickase Plasmid (h2)

sc-401595-NIC-2hGene KnockoutPuromycin0
(0)

γPAK CRISPR/Cas9 KO Plasmid (m)

sc-432435mGene KnockoutGFP0
(0)

γPAK HDR Plasmid (m)

sc-432435-HDRmHomology Directed RepairPuromycin0
(0)

γPAK Double Nickase Plasmid (m)

sc-432435-NICmGene KnockoutPuromycin0
(0)

γPAK Double Nickase Plasmid (m2)

sc-432435-NIC-2mGene KnockoutPuromycin0
(0)

PAK4 CRISPR/Cas9 KO Plasmid (h)

sc-401895hGene KnockoutGFP
2
(0)

PAK4 HDR Plasmid (h)

sc-401895-HDRhHomology Directed RepairPuromycin
2
(0)

PAK4 Double Nickase Plasmid (h)

sc-401895-NIChGene KnockoutPuromycin
2
(0)

PAK4 Double Nickase Plasmid (h2)

sc-401895-NIC-2hGene KnockoutPuromycin
2
(0)

PAK4 CRISPR/Cas9 KO Plasmid (m)

sc-427750mGene KnockoutGFP0
(0)

PAK4 HDR Plasmid (m)

sc-427750-HDRmHomology Directed RepairPuromycin0
(0)

PAK4 Double Nickase Plasmid (m)

sc-427750-NICmGene KnockoutPuromycin0
(0)

PAK4 Double Nickase Plasmid (m2)

sc-427750-NIC-2mGene KnockoutPuromycin0
(0)

PAK5 CRISPR/Cas9 KO Plasmid (h)

sc-404073hGene KnockoutGFP0
(0)

PAK5 HDR Plasmid (h)

sc-404073-HDRhHomology Directed RepairPuromycin0
(0)

PAK5 Double Nickase Plasmid (h)

sc-404073-NIChGene KnockoutPuromycin0
(0)

PAK5 Double Nickase Plasmid (h2)

sc-404073-NIC-2hGene KnockoutPuromycin0
(0)

PAK5 CRISPR/Cas9 KO Plasmid (m)

sc-433855mGene KnockoutGFP0
(0)

PAK5 HDR Plasmid (m)

sc-433855-HDRmHomology Directed RepairPuromycin0
(0)

PAK5 Double Nickase Plasmid (m)

sc-433855-NICmGene KnockoutPuromycin0
(0)

PAK5 Double Nickase Plasmid (m2)

sc-433855-NIC-2mGene KnockoutPuromycin0
(0)

PAK6 CRISPR/Cas9 KO Plasmid (h)

sc-403345hGene KnockoutGFP0
(0)

PAK6 HDR Plasmid (h)

sc-403345-HDRhHomology Directed RepairPuromycin0
(0)

PAK6 Double Nickase Plasmid (h)

sc-403345-NIChGene KnockoutPuromycin0
(0)

PAK6 Double Nickase Plasmid (h2)

sc-403345-NIC-2hGene KnockoutPuromycin0
(0)

PAK6 CRISPR/Cas9 KO Plasmid (m)

sc-431921mGene KnockoutGFP0
(0)

PAK6 HDR Plasmid (m)

sc-431921-HDRmHomology Directed RepairPuromycin0
(0)

PAK6 Double Nickase Plasmid (m)

sc-431921-NICmGene KnockoutPuromycin0
(0)

PAK6 Double Nickase Plasmid (m2)

sc-431921-NIC-2mGene KnockoutPuromycin0
(0)

PAK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

αPAK CRISPR Activation Plasmid (h)

sc-400857-ACThGene ActivationPuro, Blast, Hygro
1
(0)

αPAK CRISPR Activation Plasmid (h2)

sc-400857-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

αPAK Lentiviral Activation Particles (h)

sc-400857-LAChGene ActivationPuro, Blast, Hygro
1
(0)

αPAK Lentiviral Activation Particles (h2)

sc-400857-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

αPAK CRISPR Activation Plasmid (m)

sc-422107-ACTmGene ActivationPuro, Blast, Hygro0
(0)

αPAK CRISPR Activation Plasmid (m2)

sc-422107-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

αPAK Lentiviral Activation Particles (m)

sc-422107-LACmGene ActivationPuro, Blast, Hygro0
(0)

αPAK Lentiviral Activation Particles (m2)

sc-422107-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

βPAK CRISPR Activation Plasmid (h)

sc-401109-ACThGene ActivationPuro, Blast, Hygro0
(0)

βPAK CRISPR Activation Plasmid (h2)

sc-401109-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

βPAK Lentiviral Activation Particles (h)

sc-401109-LAChGene ActivationPuro, Blast, Hygro0
(0)

βPAK Lentiviral Activation Particles (h2)

sc-401109-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

βPAK CRISPR Activation Plasmid (m)

sc-422108-ACTmGene ActivationPuro, Blast, Hygro0
(0)

βPAK CRISPR Activation Plasmid (m2)

sc-422108-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

βPAK Lentiviral Activation Particles (m)

sc-422108-LACmGene ActivationPuro, Blast, Hygro0
(0)

βPAK Lentiviral Activation Particles (m2)

sc-422108-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

γPAK CRISPR Activation Plasmid (h)

sc-401595-ACThGene ActivationPuro, Blast, Hygro0
(0)

γPAK CRISPR Activation Plasmid (h2)

sc-401595-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

γPAK Lentiviral Activation Particles (h)

sc-401595-LAChGene ActivationPuro, Blast, Hygro0
(0)

γPAK Lentiviral Activation Particles (h2)

sc-401595-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

γPAK CRISPR Activation Plasmid (m)

sc-432435-ACTmGene ActivationPuro, Blast, Hygro0
(0)

γPAK CRISPR Activation Plasmid (m2)

sc-432435-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

γPAK Lentiviral Activation Particles (m)

sc-432435-LACmGene ActivationPuro, Blast, Hygro0
(0)

γPAK Lentiviral Activation Particles (m2)

sc-432435-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK4 CRISPR Activation Plasmid (h)

sc-401895-ACThGene ActivationPuro, Blast, Hygro
2
(0)

PAK4 CRISPR Activation Plasmid (h2)

sc-401895-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

PAK4 Lentiviral Activation Particles (h)

sc-401895-LAChGene ActivationPuro, Blast, Hygro
2
(0)

PAK4 Lentiviral Activation Particles (h2)

sc-401895-LAC-2hGene ActivationPuro, Blast, Hygro
2
(0)

PAK4 CRISPR Activation Plasmid (m)

sc-427750-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAK4 CRISPR Activation Plasmid (m2)

sc-427750-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK4 Lentiviral Activation Particles (m)

sc-427750-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAK4 Lentiviral Activation Particles (m2)

sc-427750-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK5 CRISPR Activation Plasmid (h)

sc-404073-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAK5 CRISPR Activation Plasmid (h2)

sc-404073-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAK5 Lentiviral Activation Particles (h)

sc-404073-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAK5 Lentiviral Activation Particles (h2)

sc-404073-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAK5 CRISPR Activation Plasmid (m)

sc-433855-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAK5 CRISPR Activation Plasmid (m2)

sc-433855-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK5 Lentiviral Activation Particles (m)

sc-433855-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAK5 Lentiviral Activation Particles (m2)

sc-433855-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK6 CRISPR Activation Plasmid (h)

sc-403345-ACThGene ActivationPuro, Blast, Hygro0
(0)

PAK6 CRISPR Activation Plasmid (h2)

sc-403345-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PAK6 Lentiviral Activation Particles (h)

sc-403345-LAChGene ActivationPuro, Blast, Hygro0
(0)

PAK6 Lentiviral Activation Particles (h2)

sc-403345-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PAK6 CRISPR Activation Plasmid (m)

sc-431921-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PAK6 CRISPR Activation Plasmid (m2)

sc-431921-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK6 Lentiviral Activation Particles (m)

sc-431921-LACmGene ActivationPuro, Blast, Hygro0
(0)

PAK6 Lentiviral Activation Particles (m2)

sc-431921-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PAK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

αPAK siRNA (h)

sc-29700hGene SilencingN/A
19
(0)

αPAK shRNA Plasmid (h)

sc-29700-SHhGene SilencingPuromycin
19
(0)

αPAK shRNA (h) Lentiviral Particles

sc-29700-VhGene SilencingPuromycin
19
(0)

αPAK siRNA (m)

sc-29701mGene SilencingN/A
1
(0)

αPAK shRNA Plasmid (m)

sc-29701-SHmGene SilencingPuromycin
1
(0)

αPAK shRNA (m) Lentiviral Particles

sc-29701-VmGene SilencingPuromycin
1
(0)

αPAK siRNA (r)

sc-270016rGene SilencingN/A
1
(0)

βPAK siRNA (h)

sc-36181hGene SilencingN/A
1
(0)

βPAK shRNA Plasmid (h)

sc-36181-SHhGene SilencingPuromycin
1
(0)

βPAK shRNA (h) Lentiviral Particles

sc-36181-VhGene SilencingPuromycin
1
(0)

βPAK siRNA (m)

sc-36182mGene SilencingN/A
1
(0)

βPAK shRNA Plasmid (m)

sc-36182-SHmGene SilencingPuromycin
1
(0)

βPAK shRNA (m) Lentiviral Particles

sc-36182-VmGene SilencingPuromycin
1
(0)

γPAK siRNA (h)

sc-36183hGene SilencingN/A
4
(0)

γPAK shRNA Plasmid (h)

sc-36183-SHhGene SilencingPuromycin
4
(0)

γPAK shRNA (h) Lentiviral Particles

sc-36183-VhGene SilencingPuromycin
4
(0)

γPAK siRNA (m)

sc-36184mGene SilencingN/A
1
(0)

γPAK shRNA Plasmid (m)

sc-36184-SHmGene SilencingPuromycin
1
(0)

γPAK shRNA (m) Lentiviral Particles

sc-36184-VmGene SilencingPuromycin
1
(0)

PAK4 siRNA (h)

sc-39060hGene SilencingN/A
9
(1)

PAK4 shRNA Plasmid (h)

sc-39060-SHhGene SilencingPuromycin
9
(1)

PAK4 shRNA (h) Lentiviral Particles

sc-39060-VhGene SilencingPuromycin
9
(1)

PAK4 siRNA (m)

sc-39061mGene SilencingN/A0
(0)

PAK4 shRNA Plasmid (m)

sc-39061-SHmGene SilencingPuromycin0
(0)

PAK4 shRNA (m) Lentiviral Particles

sc-39061-VmGene SilencingPuromycin0
(0)

PAK5 siRNA (h)

sc-39062hGene SilencingN/A0
(0)

PAK5 shRNA Plasmid (h)

sc-39062-SHhGene SilencingPuromycin0
(0)

PAK5 shRNA (h) Lentiviral Particles

sc-39062-VhGene SilencingPuromycin0
(0)

PAK5 siRNA (m)

sc-151996mGene SilencingN/A0
(0)

PAK5 shRNA Plasmid (m)

sc-151996-SHmGene SilencingPuromycin0
(0)

PAK5 shRNA (m) Lentiviral Particles

sc-151996-VmGene SilencingPuromycin0
(0)

PAK6 siRNA (h)

sc-39063hGene SilencingN/A
2
(0)

PAK6 shRNA Plasmid (h)

sc-39063-SHhGene SilencingPuromycin
2
(0)

PAK6 shRNA (h) Lentiviral Particles

sc-39063-VhGene SilencingPuromycin
2
(0)

PAK6 siRNA (m)

sc-44879mGene SilencingN/A
2
(0)

PAK6 shRNA Plasmid (m)

sc-44879-SHmGene SilencingPuromycin
2
(0)

PAK6 shRNA (m) Lentiviral Particles

sc-44879-VmGene SilencingPuromycin
2
(0)