Date published: 2026-4-1

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PADI6 Activators

PADI6 Activators constitute a specialized category of chemical compounds that have attracted attention in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the PADI6 gene, where PADI6 stands for Peptidyl Arginine Deiminase 6. This gene is a protein-coding element found in humans and is a member of the peptidyl arginine deiminase (PADI) family of enzymes. PADI enzymes are responsible for the post-translational modification of proteins by catalyzing the conversion of arginine residues to citrulline, a process known as citrullination. PADI6 Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the PADI6 gene, ultimately leading to an increase in the activity of the associated enzyme.

The mechanism of action of PADI6 Activators generally involves their interaction with specific regulatory elements within the PADI6 gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the PADI6 enzyme. PADI6 is believed to play a role in the citrullination of target proteins, which can have implications for various cellular processes, including gene regulation, protein-protein interactions, and immune responses. As researchers continue to explore the functions and potential implications of PADI6 activation, the development and refinement of PADI6 Activators hold promise for advancing our understanding of post-translational modifications, cellular biology, and the broader role of PADI6 in cellular functionality and molecular pathways, potentially revealing novel aspects of protein regulation and cellular responses.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

By inhibiting DNA methyltransferase, this compound could lead to demethylation and activation of gene expression, potentially affecting PADI6.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, Trichostatin A could promote chromatin relaxation and induce gene expression, which may include PADI6.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which can stimulate the transcription of various genes, possibly including PADI6.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C, leading to altered transcription factor activity and potential changes in gene expression such as PADI6.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid functions through retinoic acid receptors to modulate gene transcription, which might affect PADI6 expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol has the potential to modulate signaling pathways and influence gene expression, which could include PADI6.

3,3′-Diindolylmethane

1968-05-4sc-204624
sc-204624A
sc-204624B
sc-204624C
sc-204624D
sc-204624E
100 mg
500 mg
5 g
10 g
50 g
1 g
$37.00
$65.00
$89.00
$421.00
$681.00
$66.00
8
(1)

DIM may affect gene expression through modulation of estrogen receptor signaling, potentially impacting PADI6 expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium Butyrate, a histone deacetylase inhibitor, could potentially increase the expression of genes by altering chromatin structure, including PADI6.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium Chloride can inhibit GSK-3β, leading to changes in Wnt signaling and potentially affecting gene expression patterns, including PADI6.

Mifepristone

84371-65-3sc-203134
100 mg
$61.00
17
(1)

Mifepristone is a glucocorticoid receptor antagonist that can alter transcriptional regulation, potentially affecting PADI6 expression.