OTTMUSG00000010552 Activators
PRAME like 30 is a protein of significant importance in cellular processes, particularly in gene expression regulation and DNA integrity maintenance. Its role in the cell involves regulating gene expression through epigenetic modifications and responding to DNA damage. Activation of PRAME like 30 is crucial for maintaining proper cellular functions. The general mechanisms of activation of PRAME like 30 involve the use of various chemicals that influence epigenetic modifications or induce DNA damage. These chemicals, such as Retinoic Acid, 5-Azacytidine, Trichostatin A, Etoposide, 5-Fluorouracil (5-FU), Sodium Valproate, 3-Deazaneplanocin A (DZNep), Vorinostat, Doxorubicin, Valproic Acid, 5-Aza-2'-deoxycytidine (5-Aza-dC), and Camptothecin, act on specific pathways and cellular processes that are associated with PRAME like 30.
In summary, PRAME like 30 plays a pivotal role in cellular processes, and its activation is achieved through the use of chemicals that influence epigenetic modifications or induce DNA damage. These chemicals are essential for maintaining the proper functioning of PRAME like 30 and ensuring its role in gene expression regulation and DNA integrity maintenance.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid activates PRAME like 30 by binding to retinoic acid receptors (RARs) and forming a complex that regulates gene transcription, leading to the functional activation of the protein. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine activates PRAME like 30 by inhibiting DNA methyltransferases, resulting in DNA demethylation and the reactivation of silenced genes, including the target protein's expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A activates PRAME like 30 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target protein. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide activates PRAME like 30 by inducing DNA damage and DNA double-strand breaks, which trigger DNA repair mechanisms, resulting in the functional activation of the protein. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil activates PRAME like 30 through its incorporation into RNA and DNA, disrupting nucleic acid synthesis and leading to the induction of stress response pathways, ultimately activating the target protein. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Sodium Valproate activates PRAME like 30 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target protein. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Suberoylanilide Hydroxamic Acid activates PRAME like 30 by inhibiting histone deacetylases (HDACs), leading to increased acetylation of histones and the promotion of gene expression, including the target protein. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin activates PRAME like 30 by inducing DNA damage and DNA double-strand breaks, which trigger DNA repair mechanisms, resulting in the functional activation of the protein. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
5-Aza-dC activates PRAME like 30 by incorporating into DNA during replication, leading to DNA demethylation and the reactivation of silenced genes, including the expression of the target protein. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin activates PRAME like 30 by inhibiting topoisomerase I, causing DNA damage and single-strand breaks, which activate DNA repair pathways and ultimately lead to the functional activation of the protein. | ||||||