OPA3 Activators
OPA3 activators exert their effects on mitochondria, altering their morphology, function, or energetics, thereby indirectly modulating OPA3's function. Agents such as FCCP, Rotenone, and Oligomycin specifically target mitochondrial functions. Their ability to affect mitochondrial morphology and energetics sets a stage where OPA3, playing a role in mitochondrial membrane dynamics, can be influenced. This influence underscores the close-knit relationship between mitochondrial health and the OPA3 protein function.
Additionally, chemicals that globally impact cellular stress pathways, such as MG132, NAC, and Rapamycin, hint at the larger interconnected web of cellular signaling that weaves the fabric of OPA3 regulation. Cellular stress, particularly related to oxidative stress or proteasomal degradation, can initiate cascades that reach proteins such as OPA3. The broad mechanisms wielded by these activators reflect the intricate nature of OPA3's regulation within the cell, emphasizing its pivotal role at the crossroads of mitochondrial dynamics and cellular stress responses.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $94.00 $355.00 | 46 | |
Uncouples mitochondrial oxidative phosphorylation, potentially affecting mitochondrial morphology and OPA3 activity. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Inhibits mitochondrial electron transport, potentially modulating OPA3 activity in response to mitochondrial stress. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Inhibits ATP synthase, which can alter mitochondrial function and influence OPA3 activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium, potentially influencing OPA3 due to altered mitochondrial dynamics. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
Another uncoupler, potentially influencing mitochondrial morphology and OPA3 activity. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Inhibits vacuolar ATPase, impacting lysosomal functions which can possibly affect OPA3 activity. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can cause cellular stress and indirectly modulate proteins like OPA3. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, which can affect various cellular processes and potentially OPA3 activity. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Inhibits mitochondrial permeability transition, potentially affecting OPA3 activity. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
Acts as an antioxidant, potentially modulating OPA3 activity in response to oxidative stress. | ||||||