NPWBP Activators
The class of chemicals termed NPWBP activators predominantly consists of compounds that influence cellular signaling pathways, either directly or indirectly, resulting in the modulation of the NPWBP protein. The methods of action for these chemicals can vary extensively, from direct activation of specific enzymes, such as adenylate cyclase by Forskolin leading to increased cAMP levels, to modulating calcium signaling with ionophores like Ionomycin and A23187.
EGF exemplifies another type of activator, as it initiates the EGFR pathway, subsequently influencing multiple downstream cascades such as PI3K/Akt and MAPK. Each of these cascades incorporates a complex set of signaling molecules, transcription factors, and other proteins. In such intricate networks, a protein like NPWBP can be affected in various ways, from changes in its transcription, post-translational modifications, or even its degradation rate. Similarly, compounds like LPA demonstrate how lipid signaling molecules can initiate cascades via specific receptors. Such cascades might eventually influence proteins that are not the direct targets of the activator. The wide range of activators for NPWBP, from small molecules to growth factors, underlines the complexity and intricacy of cellular signaling networks and how they can be harnessed to modulate specific proteins.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Direct activator of adenylate cyclase, leading to increased cAMP levels. Elevated cAMP can activate multiple downstream proteins and pathways which may in turn influence the function and activity of NPWBP. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
A JNK activator that stimulates the JNK pathway. JNK activation often modulates transcription factors and gene expression, which can indirectly alter the function or expression of NPWBP. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Calcium ionophore that increases intracellular calcium concentration. Calcium signaling is a ubiquitous pathway and can have widespread effects, potentially modulating NPWBP activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PKC activator which influences many cellular processes, including the MAPK pathway, potentially influencing NPWBP activity through a cascade of signaling events. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Analog of cAMP that can activate PKA. PKA activation can lead to a cascade of events in various pathways, potentially modulating NPWBP. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Calcium ionophore, similar to Ionomycin, increases intracellular calcium levels. This can lead to activation of calcium-dependent pathways, indirectly affecting NPWBP. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $96.00 $334.00 | 50 | |
Activates the LPA receptor, leading to activation of the PLC and PI3K pathways. Activation of these pathways can have a downstream effect on NPWBP. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $158.00 $306.00 $1186.00 | 9 | |
Fatty acid synthase inhibitor. Alteration in lipid synthesis can affect membrane-related pathways and potentially modulate NPWBP activity. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
PDE4 inhibitor, leading to increased cAMP levels. Elevated cAMP affects various pathways and might indirectly modulate NPWBP. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Non-specific inhibitor of cAMP and cGMP phosphodiesterases. Elevated cyclic nucleotide levels can modulate many pathways, potentially affecting NPWBP. | ||||||