Nitrotyrosine Inhibitors
Common Nitrotyrosine Inhibitors include, but are not limited to FeTPPS CAS 90384-82-0, (-)Epicatechin CAS 490-46-0, Melatonin CAS 73-31-4, Trolox CAS 53188-07-1 and TEMPOL CAS 2226-96-2.
Nitrotyrosine inhibitors belong to a specific chemical class of compounds designed to target and inhibit the activity of proteins containing nitrotyrosine residues. Nitrotyrosine is a post-translational modification of tyrosine residues that occurs when tyrosine is nitrated by reactive nitrogen species, often found in nitric oxide and peroxynitrite. This modification can have diverse effects on protein function, including altering enzymatic activity, protein-protein interactions, and signaling pathways.
Nitrotyrosine inhibitors work by specifically targeting proteins that contain nitrotyrosine residues, interfering with the functional consequences of this modification. By doing so, these inhibitors may modulate protein activities and cellular processes influenced by nitrotyrosine-dependent signaling. Research into nitrotyrosine inhibitors is ongoing to unravel their precise mechanisms of action and explore their implications in cellular signaling and redox regulation. The study of nitrotyrosine inhibitors contributes to a deeper understanding of the intricate mechanisms governing post-translational modifications and their impact on protein function and cellular physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
FeTPPS | 90384-82-0 | sc-221611 sc-221611A | 250 mg 1 g | $215.00 $620.00 | 3 | |
Acts as an iron-based scavenger, reducing the formation of nitrotyrosine by preventing the reaction between peroxynitrite and tyrosine residues in proteins. | ||||||
(−)Epicatechin | 490-46-0 | sc-205672 sc-205672A | 1 mg 5 mg | $50.00 $135.00 | ||
Functions as a potent antioxidant, reducing peroxynitrite levels and inhibiting tyrosine nitration, potentially preventing nitrotyrosine formation in oxidative stress conditions. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $64.00 $72.00 $214.00 $683.00 $1173.00 $3504.00 | 16 | |
Acts as a free radical scavenger and antioxidant, reducing oxidative stress and peroxynitrite formation, potentially attenuating tyrosine nitration and its effects. | ||||||
Trolox | 53188-07-1 | sc-200810 sc-200810A sc-200810B sc-200810C sc-200810D | 500 mg 1 g 5 g 25 g 100 g | $37.00 $66.00 $230.00 $665.00 $1678.00 | 39 | |
Exhibits antioxidant properties, reducing peroxynitrite levels and scavenging free radicals, potentially preventing tyrosine nitration and oxidative damage in cells. | ||||||
TEMPOL | 2226-96-2 | sc-200825 | 1 g | $36.00 | 33 | |
Acts as a superoxide dismutase mimetic, reducing superoxide anions and peroxynitrite formation, and potentially attenuating tyrosine nitration and oxidative stress. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Acts as a precursor of glutathione, a cellular antioxidant, and can indirectly reduce nitrotyrosine formation by maintaining redox balance and preventing oxidative stress. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Exhibits antioxidant properties, reducing oxidative stress and peroxynitrite levels, and potentially inhibiting tyrosine nitration and its downstream effects. | ||||||
MCI-186 | 89-25-8 | sc-200806 sc-200806A | 5 g 100 g | $20.00 $31.00 | 10 | |
Acts as a free radical scavenger, reducing peroxynitrite levels and oxidative stress, potentially attenuating tyrosine nitration and its associated cellular damage. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $31.00 $61.00 | 1 | |
Displays antioxidant activity, potentially reducing peroxynitrite levels and tyrosine nitration, and protecting against oxidative stress-induced cellular damage. | ||||||
Methyl 3-(methylthio)propionate | 13532-18-8 | sc-228520 | 25 g | $29.00 | ||
Acts as a scavenger of peroxynitrite-derived radicals, reducing oxidative stress and preventing tyrosine nitration, and protecting cells from nitrotyrosine-related damage. | ||||||