Date published: 2026-4-24

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Mucin 15 Inhibitors

Mucins are large, heavily glycosylated proteins that play crucial roles in protecting and lubricating mucosal surfaces, such as those lining the gastrointestinal tract, respiratory system, and other mucous membranes throughout the body. Mucin 15, also known as MUC15, is a specific member of the mucin family that has been identified in various tissues and organs, and its functions are not yet fully understood. It is characterized by its extensive glycosylation, which contributes to its protective properties in mucosal tissues. Mucin 15 inhibitors modulate the activity of MUC15, potentially interfering with its functions. These inhibitors have the potential to influence the glycosylation patterns and structural properties of MUC15, which could, in turn, impact its interactions with other molecules and its roles in mucosal protection and lubrication. Researchers employ Mucin 15 inhibitors as valuable tools to investigate the specific functions and regulatory mechanisms of MUC15 in different cellular contexts and tissues.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Inhibits DNA methyltransferases, potentially leading to demethylation and altered gene expression including MUC15.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor that could change chromatin structure and gene expression, possibly reducing MUC15 levels.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits the PI3K/Akt pathway, which may downregulate MUC15 expression by affecting transcriptional regulation.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

Inhibits glucose transporter 1 (GLUT1), potentially decreasing energy supply and affecting protein expression including MUC15.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

A MEK inhibitor that can alter MAPK/ERK signaling, potentially impacting the transcription of various genes including MUC15.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of JNK signaling pathway, which could influence the transcription of genes related to mucin expression.

C646

328968-36-1sc-364452
sc-364452A
10 mg
50 mg
$265.00
$944.00
5
(1)

A selective p300/CBP histone acetyltransferase inhibitor, possibly affecting gene expression patterns, including MUC15.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$40.00
$120.00
$480.00
$2141.00
47
(3)

A γ-secretase inhibitor that could affect Notch signaling and thereby potentially influence MUC15 transcription.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

A proteasome inhibitor that could lead to altered signaling and transcription factor activity, potentially reducing MUC15.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

Inhibits the TGF-β receptor, which might modulate MUC15 expression by affecting TGF-β signaling pathways.