Date published: 2025-11-1

1-800-457-3801

SCBT Portrait Logo
Seach Input

MRP-S11 Inhibitors

MRP-S11 inhibitors encompass a diverse array of chemical compounds that indirectly affect the functional activity of the protein through various biochemical pathways. For instance, Verapamil serves as a calcium channel blocker, which by reducing intracellular calcium concentration, can influence calcium-dependent pathways that are crucial for MRP-S11 functionality. Similarly, Indomethacin, by inhibiting COX enzymes and diminishing prostaglandin synthesis, can impact signaling processes that regulate MRP-S11's role. Flavonoids like Quercetin and Apigenin are also noted for their kinase inhibition, which might reduce MRP-S11 activity by altering protein phosphorylation within relevant signaling cascades. Other compounds such as Progesterone and Tamoxifen, through their interaction with hormone receptors, may exert regulatory control over the expression of genes associated with MRP-S11, thus influencing its activity. Moreover, compounds like Genistein and Curcumin target protein kinases and transcription factors, respectively, and could lead to decreased MRP-S11 activity by modulating phosphorylation events and gene expression. Resveratrol's ability to interfere with cell proliferation and survival pathways offers another potential avenue for the indirect inhibition of MRP-S11. Additionally, specific kinase inhibitors, such as Imatinib and Gefitinib, might affect the MRP-S11 by altering the activation state of kinases involved in its regulation. Rapamycin, an mTOR inhibitor, could potentially downregulate cellular growth processes that support MRP-S11's function. Thus, these MRP-S11 inhibitors operate through a network of intracellular signaling adjustments, affecting pathways that are vital for the optimal activity of the protein, leading to its functional inhibition.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Verapamil

52-53-9sc-507373
1 g
$367.00
(0)

Verapamil is a calcium channel blocker that can indirectly inhibit MRP-S11 by decreasing intracellular calcium levels, which can affect calcium-dependent signaling pathways that modulate the function of MRP-S11.

Indomethacin

53-86-1sc-200503
sc-200503A
1 g
5 g
$28.00
$37.00
18
(1)

Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) pathway. By reducing prostaglandin synthesis, it may indirectly affect signaling pathways that regulate MRP-S11 activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is a flavonoid that inhibits various kinases and has antioxidant properties. It may decrease the phosphorylation state of proteins within signaling cascades that involve MRP-S11, thereby reducing its functional activity.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$51.00
$292.00
3
(1)

Progesterone interacts with nuclear hormone receptors and can modulate gene expression. This hormonal regulation may extend to genes that control the expression or function of MRP-S11.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein is a tyrosine kinase inhibitor that may interfere with phosphorylation events required for the optimal activity of MRP-S11, consequently leading to its functional inhibition.

Apigenin

520-36-5sc-3529
sc-3529A
sc-3529B
sc-3529C
sc-3529D
sc-3529E
sc-3529F
5 mg
100 mg
1 g
5 g
25 g
100 g
1 kg
$32.00
$210.00
$720.00
$1128.00
$2302.00
$3066.00
$5106.00
22
(1)

Apigenin is a bioflavonoid that can inhibit protein kinases and influence intracellular signaling pathways. This can lead to altered regulation of MRP-S11 activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol has been shown to interfere with multiple signaling pathways, including those involved in cell proliferation and survival, which might be necessary for the proper functional regulation of MRP-S11.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has multiple cellular targets and can modulate signaling pathways by affecting the activity of transcription factors and kinases, potentially leading to reduced MRP-S11 activity.

Tamoxifen

10540-29-1sc-208414
2.5 g
$256.00
18
(2)

Tamoxifen acts as a selective estrogen receptor modulator and can influence gene expression patterns. It may indirectly inhibit MRP-S11 by altering the expression of genes that interact with or regulate MRP-S11.

Imatinib

152459-95-5sc-267106
sc-267106A
sc-267106B
10 mg
100 mg
1 g
$25.00
$117.00
$209.00
27
(1)

Imatinib is a tyrosine kinase inhibitor, primarily used to inhibit BCR-ABL kinase in chronic myeloid leukemia. It could conceivably influence other kinases that control the activation state of MRP-S11.