Date published: 2025-10-10

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Progesterone (CAS 57-83-0)

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Alternate Names:
4-Pregnene-3,20-dione
Application:
Progesterone is a C-21 steroid hormone involved in uterine endothelium activity
CAS Number:
57-83-0
Purity:
≥98%
Molecular Weight:
314.46
Molecular Formula:
C21H30O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Progesterone is a steroid hormone that induces maturation and secretory activity of the uterine endothelium while suppressing ovulation. It is implicated in the etiology of breast cancer and is an activator of Progesterone Receptor. Progesterone is important for the regulation of other hormones, such as estrogen and testosterone. Progesterone also acts on the hypothalamus and pituitary gland to regulate the release of hormones, such as luteinizing hormone and follicle-stimulating hormone. Progesterone is involved in the regulation of cell growth, development, and gene expression. Progesterone is also in vitro to study the effects of hormones on the female reproductive system.


Progesterone (CAS 57-83-0) References

  1. Progesterone and the control of uterine cell proliferation and differentiation.  |  Rider, V. 2002. Front Biosci. 7: d1545-55. PMID: 12045023
  2. Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics.  |  Soyal, S., et al. 2002. Breast Cancer Res. 4: 191-6. PMID: 12223123
  3. The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis.  |  Anderson, E. 2002. Breast Cancer Res. 4: 197-201. PMID: 12223124
  4. Steroid hormone regulation of angiogenesis in the primate endometrium.  |  Albrecht, ED. and Pepe, GJ. 2003. Front Biosci. 8: d416-29. PMID: 12456304
  5. Progesterone receptors--animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer.  |  Lanari, C. and Molinolo, AA. 2002. Breast Cancer Res. 4: 240-3. PMID: 12473170
  6. MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association.  |  Qiu, M. and Lange, CA. 2003. J Steroid Biochem Mol Biol. 85: 147-57. PMID: 12943699
  7. Progesterone receptors: form and function in brain.  |  Brinton, RD., et al. 2008. Front Neuroendocrinol. 29: 313-39. PMID: 18374402
  8. Boots for Achilles: progesterone's reduction of cholesterol is a second-order adaptation.  |  Amir, D. and Fessler, DM. 2013. Q Rev Biol. 88: 97-116. PMID: 23909226
  9. Progesterone and abnormal uterine bleeding/menstrual disorders.  |  Jewson, M., et al. 2020. Best Pract Res Clin Obstet Gynaecol. 69: 62-73. PMID: 32698992
  10. Progesterone modulates neuronal excitability bidirectionally.  |  Kapur, J. and Joshi, S. 2021. Neurosci Lett. 744: 135619. PMID: 33421486
  11. Developmental expression of genes involved in progesterone synthesis, metabolism and action during the post-natal cerebellar myelination.  |  Mancino, DN., et al. 2021. J Steroid Biochem Mol Biol. 207: 105820. PMID: 33465418
  12. Divergent evolution of progesterone and mineralocorticoid receptors in terrestrial vertebrates and fish influences endocrine disruption.  |  Baker, ME. 2022. Biochem Pharmacol. 198: 114951. PMID: 35149051
  13. Progesterone and the neural mechanisms of hamster sexual behavior.  |  DeBold, JF. and Frye, CA. 1994. Psychoneuroendocrinology. 19: 563-79. PMID: 7938355

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Progesterone, 1 g

sc-296138A
1 g
$20.00

Progesterone, 5 g

sc-296138
5 g
$51.00

Progesterone, 50 g

sc-296138B
50 g
$292.00

Buen dia !! , mi consulta es sobre si progesterona cas :57-83-0 es bioidentica, gracais , saludos.

Asked by: SARA 2025
Thank you for your question. Progesterone (CAS 57-83-0) sc-296138 is bioidentical. Please note that all of our products are of technical grade quality and are for research use only.
Answered by: Tech Support Europe
Date published: 2025-05-21
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Rated 4 out of 5 by from I will rate this product a 4 and rate 5I will rate this product a 4 and rate 5 for your logistics, customer service and support.
Date published: 2015-04-20
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Progesterone is rated 4.0 out of 5 by 1.
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