MMP-10 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $160.00 $319.00 | 3 | |
Actinonin is a potent inhibitor of MMP-10, showcasing a unique mechanism of action through its ability to bind selectively to the enzyme's active site. This binding induces conformational changes that hinder substrate recognition and processing. The compound's molecular structure facilitates specific interactions, including van der Waals forces and electrostatic interactions, which enhance its inhibitory efficacy. Additionally, Actinonin's kinetic profile reveals a notable impact on the enzyme's turnover rate, further underscoring its role in modulating proteolytic activity. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $165.00 $214.00 $396.00 $617.00 $4804.00 | 19 | |
Marimastat is a broad-spectrum MMP inhibitor that binds to the zinc ion in the active site of MMPs, thereby preventing the enzymatic activity of MMP-10. | ||||||
NNGH | 161314-17-6 | sc-222075 | 5 mg | $95.00 | 2 | |
NNGH serves as a selective inhibitor of MMP-10, characterized by its ability to disrupt enzyme-substrate interactions through unique hydrogen bonding and hydrophobic interactions. This compound alters the enzyme's conformation, effectively blocking the catalytic site and reducing enzymatic activity. Its distinct reaction kinetics highlight a competitive inhibition mechanism, where NNGH's presence significantly decreases the rate of substrate turnover, thereby influencing proteolytic pathways. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $75.00 $265.00 | 55 | |
Ilomastat, also known as GM6001, inhibits MMP-10 by chelating the zinc ion in its active site, which is essential for its proteolytic activity. | ||||||
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $175.00 $370.00 | 24 | |
Batimastat is a synthetic inhibitor that binds to the active site of MMP-10, obstructing its interaction with substrates. | ||||||
Prinomastat | 192329-42-3 | sc-507449 | 5 mg | $190.00 | ||
Prinomastat selectively inhibits MMP-10 by binding to the zinc-binding site, reducing its proteolytic activity. | ||||||
SB-3CT | 292605-14-2 | sc-205847 sc-205847A | 1 mg 5 mg | $100.00 $380.00 | 15 | |
SB-3CT targets the gelatinase subclass of MMPs, including MMP-10, by irreversibly binding to the zinc-containing active site. | ||||||
TAPI-1 | 171235-71-5 | sc-222337 | 1 mg | $656.00 | 15 | |
TAPI-1 is a broad-spectrum inhibitor affecting multiple MMPs including MMP-10, interfering with the proteolytic cleavage of substrate proteins. | ||||||
Doxycycline Hyclate | 24390-14-5 | sc-204734B sc-204734 sc-204734A sc-204734C | 100 mg 1 g 5 g 25 g | $26.00 $49.00 $105.00 $190.00 | 25 | |
Doxycycline, while primarily an antibiotic, has been found to inhibit MMP-10 activity by chelating the zinc ion at its active site. | ||||||
Minocycline, Hydrochloride | 13614-98-7 | sc-203339 sc-203339A sc-203339B sc-203339C sc-203339D sc-203339E sc-203339F | 50 mg 250 mg 1 g 2.5 g 10 g 100 g 1 kg | $52.00 $168.00 $275.00 $622.00 $1234.00 $5722.00 $24490.00 | 36 | |
Minocycline, another antibiotic, exhibits MMP-10 inhibitory activity by interfering with the zinc-dependent enzymatic mechanism of MMP-10. | ||||||