Misato Inhibitors refer to a specific category of chemical compounds designed to target and modulate the activity of the protein Misato. Misato is a protein that plays a crucial role in the process of cell division, particularly during mitosis. Cell division is a fundamental process in which a parent cell divides into two daughter cells, ensuring the growth, development, and maintenance of multicellular organisms. Misato, which is conserved in various organisms, including humans, contributes to the proper organization and function of the microtubule-based mitotic spindle apparatus. This spindle apparatus helps segregate chromosomes accurately during cell division, ensuring that each daughter cell receives the correct complement of genetic material. Inhibitors of Misato are developed to interact with this specific protein, potentially influencing its function and disrupting normal cell division processes.
Structurally, Misato inhibitors are carefully designed to engage specific regions or binding sites on the Misato protein. This interaction can disrupt the protein's normal functioning, potentially affecting its role in microtubule organization, spindle assembly, or chromosome segregation. The mechanisms by which Misato inhibitors exert their effects can vary, but their primary goal is to serve as valuable tools for researchers investigating the intricate process of cell division. Studying the biochemical and functional aspects of Misato and its modulation by inhibitors can provide insights into the mechanisms that govern accurate chromosome segregation during cell division, contributing to a deeper understanding of fundamental cellular processes and potential applications in various fields of biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Known to inhibit mitochondrial division by targeting dynamin-related protein 1 (DRP1). | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
Uncouples mitochondrial oxidative phosphorylation, potentially impacting mitochondrial morphology. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
An inhibitor of ATP synthase, affecting mitochondrial ATP production. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Inhibits mitochondrial complex I, potentially altering mitochondrial dynamics. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
A complex III inhibitor that can affect mitochondrial function. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $94.00 $355.00 | 46 | |
Another uncoupling agent for mitochondrial oxidative phosphorylation. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $250.00 | 3 | |
Acts as a potassium ionophore, disrupting mitochondrial membrane potential. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $170.00 $385.00 | 3 | |
Inhibits mitochondrial peptide deformylase affecting mitochondrial protein maturation. | ||||||
3-Nitropropionic acid | 504-88-1 | sc-214148 sc-214148A | 1 g 10 g | $82.00 $459.00 | ||
Inhibits mitochondrial complex II. | ||||||
2-Thenoyltrifluoroacetone | 326-91-0 | sc-251801 | 5 g | $37.00 | 1 | |
Another inhibitor of mitochondrial complex II. | ||||||