MIBP1 inhibitors belong to a distinct chemical class characterized by their ability to selectively target and inhibit the activity of MIBP1, a specific protein within the cellular environment. MIBP1, short for Mitotic Interactor and Borealin-Related Protein 1, plays a crucial role in cellular processes, particularly in the regulation of cell division and mitosis. The inhibitors designed to interact with MIBP1 share a common structural motif that allows them to bind to the active site of the protein, modulating its function and impeding the normal progression of cell cycle events.
MIBP1 inhibitors often feature a combination of aromatic and heterocyclic moieties, enabling them to form specific interactions with the target protein. The chemical modifications on these inhibitors are meticulously designed to optimize binding affinity and selectivity for MIBP1, ensuring minimal interference with other cellular components. Researchers leverage structural biology techniques, such as X-ray crystallography and nuclear magnetic resonance spectroscopy, to elucidate the precise binding mechanisms between MIBP1 and its inhibitors. MIBP1 inhibitors represents a significant area of interest in chemical biology and drug discovery, as their targeted interference with cell division processes could have implications in various cellular contexts. Understanding the structural intricacies of these inhibitors and their interaction with MIBP1 opens avenues for the development of innovative strategies to manipulate cellular pathways for research purposes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates transcription factors and could alter HIVEP2 expression indirectly. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Affects signaling pathways, potentially altering HIVEP2's role in gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Isoflavone that may modulate transcription factor activity, possibly affecting HIVEP2. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Flavonoid that can influence transcription factor dynamics and thereby affect HIVEP2. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can indirectly affect transcription factor activities linked to HIVEP2. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that could modify transcriptional regulation involving HIVEP2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can influence various transcription factors, potentially including HIVEP2. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAP kinase inhibitor that might have an impact on HIVEP2's role in stress response pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A compound that might alter DNA methylation and indirectly affect HIVEP2 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
HDAC inhibitor that could indirectly influence HIVEP2 by altering chromatin structure. | ||||||