Date published: 2026-1-30

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MBNL Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MBNL Antibodies for investigating MBNL proteins in cellular processes. MBNL Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).MBNL proteins, or Muscleblind-like proteins, regulate alternative splicing and significantly influence muscle development and function. MBNL dysregulation has been linked to various diseases, including myotonic dystrophy, leading to substantial pathological effects. Research focused on MBNL proteins continues to reveal their importance in normal physiology and disease mechanisms.Muscleblind-like proteins have emerged as key factors in RNA processing and cellular development. Ongoing studies highlight MBNL's involvement in tissue-specific alternative splicing patterns. Recent discoveries have expanded understanding of MBNL's role beyond muscle tissues to include regulation in various cell types. Advanced research techniques have revealed new insights into MBNL's molecular interactions and cellular distribution patterns. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of MBNL proteins and their impact on human health.

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MBNL Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MBNL1 Antibody (3A4)

sc-47740mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
32
(10)

MBNL1 Antibody (4A8)

sc-136165mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h
2
(1)

MBNL1 Antibody (D-4)

sc-515374mouse IgG111-100 (h)WB, IP, IF, ELISAm, r, h
2
(0)

MBNL1/2 Antibody (5F9)

sc-136166mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h

new

(1)

MBNL2 Antibody (3B4)

sc-136167mouse IgG2b κ(h)WB, IP, IF, IHC(P)m, r, h
26
(7)

MBNL2 Antibody (D-1)

sc-365104mouse IgG1 κ101-181 (h)WB, IP, IF, ELISAm, r, h

new

(3)

MBNL3 Antibody (5A11)

sc-136168mouse IgG1 κFL (h)WB, IF, IHC(P)m, r, h
1
(1)

MBNL CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBNL1 CRISPR/Cas9 KO Plasmid (h)

sc-402194hGene KnockoutGFP0
(0)

MBNL1 HDR Plasmid (h)

sc-402194-HDRhHomology Directed RepairPuromycin0
(0)

MBNL1 Double Nickase Plasmid (h)

sc-402194-NIChGene KnockoutPuromycin0
(0)

MBNL1 Double Nickase Plasmid (h2)

sc-402194-NIC-2hGene KnockoutPuromycin0
(0)

MBNL2 HDR Plasmid (h2)

sc-401921-HDR-2hHomology Directed RepairPuromycin0
(0)

MBNL2 Double Nickase Plasmid (h)

sc-401921-NIChGene KnockoutPuromycin0
(0)

MBNL2 Double Nickase Plasmid (h2)

sc-401921-NIC-2hGene KnockoutPuromycin0
(0)

MBNL3 CRISPR/Cas9 KO Plasmid (h)

sc-406573hGene KnockoutGFP0
(0)

MBNL CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBNL1 CRISPR Activation Plasmid (m)

sc-425296-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MBNL1 Lentiviral Activation Particles (m)

sc-425296-LACmGene ActivationPuro, Blast, Hygro0
(0)

MBNL2 CRISPR Activation Plasmid (h)

sc-401921-ACThGene ActivationPuro, Blast, Hygro0
(0)

MBNL siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBNL1 siRNA (h)

sc-60988hGene SilencingN/A
3
(0)

MBNL1 shRNA Plasmid (h)

sc-60988-SHhGene SilencingPuromycin
3
(0)

MBNL1 shRNA (h) Lentiviral Particles

sc-60988-VhGene SilencingPuromycin
3
(0)

MBNL1 siRNA (m)

sc-60989mGene SilencingN/A0
(0)

MBNL1 shRNA Plasmid (m)

sc-60989-SHmGene SilencingPuromycin0
(0)

MBNL1 shRNA (m) Lentiviral Particles

sc-60989-VmGene SilencingPuromycin0
(0)

MBNL2 siRNA (h)

sc-60990hGene SilencingN/A
1
(0)

MBNL2 shRNA Plasmid (h)

sc-60990-SHhGene SilencingPuromycin
1
(0)

MBNL2 shRNA (h) Lentiviral Particles

sc-60990-VhGene SilencingPuromycin
1
(0)

MBNL2 siRNA (m)

sc-60991mGene SilencingN/A0
(0)

MBNL2 shRNA Plasmid (m)

sc-60991-SHmGene SilencingPuromycin0
(0)

MBNL2 shRNA (m) Lentiviral Particles

sc-60991-VmGene SilencingPuromycin0
(0)

MBNL3 siRNA (h)

sc-60992hGene SilencingN/A0
(0)

MBNL3 shRNA Plasmid (h)

sc-60992-SHhGene SilencingPuromycin0
(0)

MBNL3 shRNA (h) Lentiviral Particles

sc-60992-VhGene SilencingPuromycin0
(0)

MBNL3 siRNA (m)

sc-60993mGene SilencingN/A0
(0)

MBNL3 shRNA Plasmid (m)

sc-60993-SHmGene SilencingPuromycin0
(0)

MBNL3 shRNA (m) Lentiviral Particles

sc-60993-VmGene SilencingPuromycin0
(0)