Date published: 2026-5-30

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MASGP-BP Inhibitors

MASGP-BP inhibitors, short for "Membrane-Associated Serine Protease Growth Factor-Binding Protein Inhibitors," belong to a specialized chemical class that targets specific molecular components involved in cellular growth and signaling pathways. These inhibitors are designed to interact with membrane-associated serine protease growth factor-binding proteins (MASGP), which play a pivotal role in the regulation of various cellular processes. MASGP-BP inhibitors are characterized by their ability to modulate the activity of MASGP proteins, ultimately influencing downstream cellular functions.

At the molecular level, MASGP-BP inhibitors are typically small organic molecules that are designed to interact with specific binding sites on MASGP proteins. These inhibitors can disrupt the normal function of MASGP proteins by binding to them, either blocking their interaction with growth factors or altering their enzymatic activity. This interference can result in the modulation of signaling pathways associated with cellular growth, differentiation, and proliferation. By targeting MASGP proteins, these inhibitors provide researchers with a valuable tool to better understand the intricate mechanisms governing cellular behavior. Moreover, the development and study of MASGP-BP inhibitors may hold promise in various research areas, including cancer biology and cell biology, by shedding light on the fundamental processes that underlie cell growth and development.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

JQ1 is a small molecule that inhibits BET bromodomain proteins, potentially downregulating transcription of certain genes.

RGFP966

1357389-11-7sc-507300
5 mg
$115.00
(0)

This compound selectively inhibits HDAC3, which can alter the chromatin structure and affect gene expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide has been shown to inhibit transcriptional activity by affecting RNA polymerase II.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A cytidine analog that incorporates into DNA and RNA and can disrupt DNA methylation, affecting gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

5-Aza-2′-Deoxycytidine is incorporated into DNA during replication and can affect DNA methylation patterns.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

A histone deacetylase inhibitor that can change chromatin structure and gene expression.

Romidepsin

128517-07-7sc-364603
sc-364603A
1 mg
5 mg
$218.00
$634.00
1
(1)

It is another histone deacetylase inhibitor that alters the expression of various genes.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A compound that inhibits histone deacetylase, leading to altered chromatin and gene expression profiles.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$210.00
$305.00
$495.00
10
(1)

PARP inhibitor that, while primarily involved in DNA repair, also influences gene expression and chromatin structure.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$90.00
$212.00
24
(2)

An HDAC inhibitor that can affect the acetylation status of histones and other proteins, impacting gene expression.