LYPD3 Activators
The category of LYPD3 activators primarily contains chemical agents that function within crucial cellular pathways, casting an indirect influence on LYPD3's activity. A significant factor in understanding these activators is the insight into LYPD3's involvement in processes such as cell migration and adhesion. Chemicals like Retinoic Acid are instrumental in gene expression modulation, targeting genes within the axis of cell migration and adhesion. The resultant modulation, driven by Retinoic Acid, can alter the expression or functional landscape of LYPD3, effectively positioning it as an indirect activator.
Furthermore, the cellular energy regulation centerpoint, AMPK, becomes a focal pathway when considering LYPD3's association with cell migration. The activation of AMPK by agents like AICAR serves to shape the energy metabolism of the cell, and, in turn, processes that are energy-dependent, such as cell migration. This cascading influence can trickle down to proteins like LYPD3, making AICAR an indirect modulator. The recurring theme of cyclic nucleotides, particularly cAMP, is hard to ignore in the realm of cellular signaling. Chemicals like Rolipram and Dibutyryl-cAMP, which either elevate or mimic cAMP, steer several cellular signaling cascades. Such cascades, if intertwined with the functional domain of LYPD3, can be indirectly influenced by these chemicals. On similar lines, the intricate network of protein kinases, epitomized by PKC, serves as an avenue of LYPD3 modulation. Chemicals like PMA, which activate PKC, might regulate cellular events wherein LYPD3 plays a role, effectively marking PMA as an indirect LYPD3 activator.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid modulates gene expression through retinoic acid receptors. Since LYPD3 is associated with cell migration and adhesion, modulating genes in this axis with Retinoic Acid can indirectly influence LYPD3's expression and function. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, central to cellular energy regulation. Given LYPD3's link to cell migration, influencing energy metabolism with AICAR can indirectly impact processes where LYPD3 is essential. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
By inhibiting PDE4 and raising cAMP levels, it impacts cellular signaling. A rise in cAMP can indirectly influence LYPD3 if it's associated with cAMP-driven cellular responses. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Increases intracellular cAMP, affecting various signaling cascades. An elevation in cAMP may indirectly modulate LYPD3's function in cell migration and adhesion. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates PKC, which has broad cellular impacts. PKC activation can potentially regulate cellular processes involving LYPD3, hence modulating its activity. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Raises both cAMP and cGMP levels by inhibiting PDE. The enhanced levels of these cyclic nucleotides can affect signaling pathways and processes associated with LYPD3. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $57.00 $184.00 $867.00 | 10 | |
By inhibiting GSK3β, BIO can affect the Wnt/β-catenin pathway. If LYPD3 is interlinked with this pathway, its function can be indirectly impacted by BIO. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
Impacts Notch signaling by inhibiting γ-secretase. LYPD3's function in cell migration and adhesion can be indirectly modulated if it operates within or alongside the Notch pathway. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
As a phosphatase inhibitor, it alters phosphorylation dynamics. If LYPD3's function or associated processes are regulated by phosphorylation, Okadaic Acid can indirectly modulate its activity. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Modulates gene expression by influencing histone acetylation. VPA's impact on the transcription landscape can indirectly modulate LYPD3 if it affects genes or processes linked to LYPD3. | ||||||