LYPD3 Inhibitors
The chemical class of LYPD3 Inhibitors encompasses a range of molecules with inhibitory action either directly or indirectly related to LYPD3's functional involvements. The specific biochemical interactions can vary greatly, dependent on the particular pathway or cellular process in which LYPD3 is implicated. Compounds such as U0126 and PD98059 focus on the ERK/MAPK pathway, effectively downregulating any ERK-dependent activation of LYPD3. On the other hand, inhibitors like Y-27632 and NSC23766 act on the Rho and Rac GTPases, respectively.
If LYPD3 is involved in actin cytoskeleton rearrangements or cell motility regulated by these GTPases, its function can be impeded by these inhibitors. Another class of inhibitors targets the PI3K/Akt signaling cascade; LY294002 and Wortmannin are primary examples. These inhibitors could suppress LYPD3's activities if it operates in cell survival pathways that are governed by PI3K/Akt signaling. Overall, each chemical inhibitor in this list serves to target a specific pathway or cellular function, where LYPD3 may be involved, thereby providing a range of options for modulating its activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a specific Rho-associated kinase (ROCK) inhibitor that affects actin organization. If LYPD3 is implicated in actin rearrangement, its biological functions can be suppressed by Y-27632. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective p38 MAPK inhibitor. If LYPD3 has a role in inflammatory responses regulated by p38 MAPK, this inhibitor can suppress its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits phosphatidylinositol 3-kinase (PI3K), thus suppressing Akt activation. If LYPD3 is involved in cellular survival pathways governed by PI3K/Akt, its activity can be hindered. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor. If LYPD3 operates in any PI3K-related signaling cascade, this inhibitor can reduce its function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits c-Jun N-terminal kinase (JNK), affecting cellular stress responses. If LYPD3's activity is JNK-dependent, it can be inhibited by this chemical. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
NSC23766 is a Rac1 GTPase inhibitor. If LYPD3 is involved in Rac1-dependent cellular processes such as migration, this compound can inhibit its function. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
ML141 is a selective inhibitor of Cdc42 GTPase. If LYPD3 is involved in cellular mechanisms reliant on Cdc42, its activity can be inhibited. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 selectively inhibits MEK1 activation and the phosphorylation of ERK1/2. If LYPD3 functions downstream or parallel to this, its function can be suppressed. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
BAPTA-AM is a cell-permeable Ca2+ chelator. If LYPD3 is involved in calcium-dependent signaling, this can inhibit its functional activities. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
KN-93 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII). If LYPD3 operates in CaMKII-dependent pathways, this compound can inhibit its function. | ||||||