Date published: 2025-10-26

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LOC643678 Inhibitors

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Items 1 to 10 of 19 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

A non-selective protein kinase inhibitor that can inhibit protein kinases, potentially altering signaling pathways that the protein LOC643678 may be involved in.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$76.00
$265.00
80
(4)

Increases intracellular calcium concentration, activating calmodulin-dependent kinases which can modify proteins such as LOC643678 if it is calcium-sensitive.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

Activates protein kinase C (PKC), which can phosphorylate substrates including LOC643678 if it is PKC-responsive.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$159.00
$315.00
$598.00
34
(1)

Non-selective inhibitor of phosphodiesterases, increases cAMP by preventing its breakdown, enhancing PKA activity and thus can activate LOC643678 if it is under cAMP regulation.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

An inhibitor of p38 MAP kinase. If LOC643678 is activated by stress-activated protein kinases, SB203580 can impede its activity indirectly.

SB-216763

280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$70.00
$198.00
18
(1)

Glycogen synthase kinase 3 (GSK-3) inhibitor, which can increase the activity of proteins regulated by the GSK-3 signaling pathway, including LOC643678 if it is a downstream effector.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$62.00
$112.00
$214.00
$342.00
74
(2)

An EGFR inhibitor that can impede signaling pathways involving epidermal growth factor receptor. If LOC643678 is part of the EGFR signaling cascade, Gefitinib can indirectly inhibit it.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

An inhibitor of MEK1, which can block the MAPK/ERK pathway. If LOC643678 is regulated through this pathway, PD98059 can indirectly inhibit its function.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Inhibits MEK, which may lead to an increase in proteins regulated by the ERK/MAPK pathway, including LOC643678 if it is downstream of this pathway.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

A PI3K inhibitor like LY294002, but more potent and irreversible. If LOC643678 operates within the PI3K/AKT pathway, Wortmannin can indirectly inhibit its activity.