LOC643678 Inhibitors
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Items 1 to 10 of 19 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A non-selective protein kinase inhibitor that can inhibit protein kinases, potentially altering signaling pathways that the protein LOC643678 may be involved in. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium concentration, activating calmodulin-dependent kinases which can modify proteins such as LOC643678 if it is calcium-sensitive. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), which can phosphorylate substrates including LOC643678 if it is PKC-responsive. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Non-selective inhibitor of phosphodiesterases, increases cAMP by preventing its breakdown, enhancing PKA activity and thus can activate LOC643678 if it is under cAMP regulation. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
Glycogen synthase kinase 3 (GSK-3) inhibitor, which can increase the activity of proteins regulated by the GSK-3 signaling pathway, including LOC643678 if it is a downstream effector. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
An inhibitor of p38 MAP kinase. If LOC643678 is activated by stress-activated protein kinases, SB203580 can impede its activity indirectly. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
An EGFR inhibitor that can impede signaling pathways involving epidermal growth factor receptor. If LOC643678 is part of the EGFR signaling cascade, Gefitinib can indirectly inhibit it. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK1, which can block the MAPK/ERK pathway. If LOC643678 is regulated through this pathway, PD98059 can indirectly inhibit its function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Inhibits MEK, which may lead to an increase in proteins regulated by the ERK/MAPK pathway, including LOC643678 if it is downstream of this pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor like LY294002, but more potent and irreversible. If LOC643678 operates within the PI3K/AKT pathway, Wortmannin can indirectly inhibit its activity. | ||||||