Date published: 2025-10-25

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LOC284023 Activators

Resveratrol and 1,1-Dimethylbiguanide, Hydrochloride activate SIRT1 and AMPK, respectively, both of which are involved in regulating gene expression and protein function. Lithium chloride's inhibition of GSK-3β can lead to the activation of Wnt signaling, a pathway known to play a role in gene transcription and protein regulation. Curcumin and sulforaphane exert effects on NF-κB and Nrf2 pathways, respectively, which are pivotal in the cellular response to stress and can lead to changes in the expression and activity of various proteins.

Compounds like quercetin and epicatechin, known for their antioxidant properties, are involved in modulating cellular signaling pathways that can influence gene expression. Piperine is of interest due to its potential to increase the bioavailability of other compounds, indirectly affecting protein activity. Genistein's ability to inhibit tyrosine kinases can have downstream effects on signaling pathways that govern gene expression and protein activity. Capsaicin, the active component in chili peppers, activates the TRPV1 receptor and can lead to alterations in cellular signaling and gene expression. Kaempferol and indole-3-carbinol interact with various cellular targets, including estrogen receptors, which can have downstream effects on gene expression and protein function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Activates SIRT1, which can influence gene expression and protein activity.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Inhibits GSK-3β, leading to activation of Wnt signaling and possible changes in protein expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Modulates multiple signaling pathways, including NF-κB, which can affect gene expression.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$42.00
$62.00
$153.00
$255.00
$500.00
$30.00
37
(1)

Activates AMPK, influencing metabolic pathways and gene expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Influences Nrf2 pathway, which may affect gene expression and protein activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Modulates signaling pathways and gene expression, potentially through its antioxidant effects.

Piperine

94-62-2sc-205809
sc-205809A
5 g
25 g
$36.00
$143.00
3
(0)

May increase the bioavailability of various compounds and influence multiple signaling pathways.

(−)Epicatechin

490-46-0sc-205672
sc-205672A
1 mg
5 mg
$50.00
$135.00
(1)

Affects nitric oxide production and may influence protein function and gene expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Acts as a protein tyrosine kinase inhibitor, affecting signaling pathways and gene expression.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$94.00
$173.00
$255.00
$423.00
26
(1)

Activates TRPV1, which could lead to changes in cellular signaling and gene expression.