Date published: 2025-10-12

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Piperine (CAS 94-62-2)

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Alternate Names:
1-Piperoylpiperidine
Application:
Piperine is a black pepper extract TRPV1 activator
CAS Number:
94-62-2
Purity:
≥95%
Molecular Weight:
285.34
Molecular Formula:
C17H19NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Piperine is an alkaloid that has been studied in agricultural and chemical. It is the compound responsible for the pungency of black pepper. Some may also examine piperine′s role as a bioavailability enhancer for certain nutrients and its effect on the metabolism of various substances. In agriculture, studies focus on piperine′s potential as a pesticide, given its insecticidal properties. Piperine serves as a model compound in studies of alkaloid biosynthesis and in the exploration of organic synthesis methods due to its relatively simple structure. Its role in modifying the thermogenic processes of organisms is another area of interest, which has implications for understanding metabolic regulation. Piperine′s interaction with chemical-metabolizing enzymes is also a subject of chemical, as it can influence the breakdown and absorption of various compounds.


Piperine (CAS 94-62-2) References

  1. Black pepper and its pungent principle-piperine: a review of diverse physiological effects.  |  Srinivasan, K. 2007. Crit Rev Food Sci Nutr. 47: 735-48. PMID: 17987447
  2. Piper nigrum and piperine: an update.  |  Meghwal, M. and Goswami, TK. 2013. Phytother Res. 27: 1121-30. PMID: 23625885
  3. Piperine and Its Role in Chronic Diseases.  |  Derosa, G., et al. 2016. Adv Exp Med Biol. 928: 173-184. PMID: 27671817
  4. Piperine as a Potential Anti-cancer Agent: A Review on Preclinical Studies.  |  Manayi, A., et al. 2018. Curr Med Chem. 25: 4918-4928. PMID: 28545378
  5. Piperine: role in prevention and progression of cancer.  |  Zadorozhna, M., et al. 2019. Mol Biol Rep. 46: 5617-5629. PMID: 31273611
  6. Propitious Profile of Peppery Piperine.  |  Bakshi, H., et al. 2021. Curr Mol Pharmacol. 14: 477-486. PMID: 32703146
  7. Piperine protects LPS-induced mastitis by inhibiting inflammatory response.  |  Yu, S., et al. 2020. Int Immunopharmacol. 87: 106804. PMID: 32707496
  8. Piperine: A review of its biological effects.  |  Haq, IU., et al. 2021. Phytother Res. 35: 680-700. PMID: 32929825
  9. A review on the bioavailability, bio-efficacies and novel delivery systems for piperine.  |  Zhang, W., et al. 2021. Food Funct. 12: 8867-8881. PMID: 34528635
  10. Dietary Piperine is Transferred into the Milk of Nursing Mothers.  |  N Diaye, K., et al. 2021. Mol Nutr Food Res. 65: e2100508. PMID: 34633734
  11. The efficacy of curcumin-piperine co-supplementation on clinical symptoms, duration, severity, and inflammatory factors in COVID-19 outpatients: a randomized double-blind, placebo-controlled trial.  |  Askari, G., et al. 2022. Trials. 23: 472. PMID: 35668500
  12. Synergistic Effect of Piperine and its Derivatives: A Comprehensive Review.  |  Saini, N., et al. 2023. Curr Drug Res Rev. 15: 105-121. PMID: 36321239
  13. Effect of Piperine on Saltiness Perception.  |  Moss, R., et al. 2023. Foods. 12: PMID: 36673388

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Piperine, 5 g

sc-205809
5 g
$36.00

Piperine, 25 g

sc-205809A
25 g
$143.00