LOC100041354 Inhibitors
LOC100041354 inhibitors function through several mechanisms, for example, Wortmannin and LY294002 target the PI3K/Akt pathway, a critical axis in cellular signaling, which can control various aspects of LOC100041354 function, including its activation state and its role in cell survival. Triciribine directly inhibits Akt, further impacting the signaling cascade that LOC100041354 is a part of. PD0332991 and ZM-447439 disrupt cell cycle regulation and mitotic progression, respectively, suggesting that LOC100041354 may play a role in cell division. SB431542 and BAY 11-7082 target the TGF-β and NF-κB pathways, which are involved in controlling cell differentiation and immune responses, indicating that LOC100041354 could be a regulatory protein within these pathways.
SP600125 and U0126 inhibit the JNK and MEK enzymes, pointing to LOC100041354's involvement in the MAPK/ERK pathway that governs cell proliferation and differentiation. PP2 affects the Src family kinases, hinting at LOC100041354's potential association with signaling related to cellular structure and adhesion. DAPT, by inhibiting γ-secretase, suggests that processing events may activate or deactivate LOC100041354. MG132 blocks proteasome activity, which can influence the stability and turnover of LOC100041354, indicating its role in protein degradation pathways.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Inhibits PI3K, which could regulate LOC100041354 if it's part of the PI3K/Akt signaling pathway. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $104.00 $141.00 | 14 | |
Inhibits Akt, which could affect LOC100041354 activity if it's downstream of Akt signaling. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
Inhibits CDK4/6, potentially controlling LOC100041354 if it's related to cell cycle regulation. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
Inhibits Aurora kinases, which could alter LOC100041354 if it's involved in mitotic progression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β receptor, which could modulate LOC100041354 activity in the TGF-β signaling pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Inhibits NF-κB pathway, which could regulate LOC100041354 if it's part of this signaling cascade. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which could affect LOC100041354 activity in the JNK signaling pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, which could regulate LOC100041354 activity if it interacts with PI3K/Akt signaling. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Inhibits Src family kinases, which could modulate LOC100041354 if it's affected by Src signaling. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
Inhibits γ-secretase, which could alter LOC100041354 if it's processed by this enzyme. | ||||||