LOC100041343 Inhibitors
LOC100041343 Inhibitors like Wortmannin and PIK-75 target PI3K, while Triciribine blocks Akt, collectively suppressing the PI3K/Akt/mTOR pathway crucial for cell growth and survival. If LOC100041343 is regulated by this pathway, these inhibitors could diminish its activity. MEK inhibitors such as SL327 and PD0325901 reduce ERK pathway signaling, which determines cell fate, potentially decreasing LOC100041343 activity if linked to ERK.
Kinase-targeting compounds, LY333531 and Roscovitine, inhibit PKC and CDKs respectively, affecting proteins involved in these pathways which could influence LOC100041343 if it's a substrate. IC261, a CK1 inhibitor, and SP600125, a JNK inhibitor, could modify the activity of proteins in cell cycle and stress response pathways, impacting LOC100041343 if it's associated with CK1 or JNK. SB216763 and SB431542 block GSK-3β and TGF-β receptor kinase, possibly affecting Wnt and TGF-β pathways, and by extension, LOC100041343 activity if it operates within these.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, preventing Akt activation, which can suppress downstream targets in the PI3K/Akt/mTOR pathway, affecting LOC100041343 activity if it is regulated by this pathway. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Inhibits Akt, reducing the phosphorylation and activity of downstream proteins within the Akt signaling pathway, potentially decreasing LOC100041343 activity. | ||||||
SL-327 | 305350-87-2 | sc-200685 sc-200685A | 1 mg 10 mg | $107.00 $332.00 | 7 | |
Inhibits MEK1/2, leading to decreased ERK pathway activation and could downregulate LOC100041343 if it is modulated by the ERK pathway. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $92.00 $281.00 | 6 | |
Inhibits protein kinase C, altering the phosphorylation of proteins involved in PKC-mediated pathways, possibly affecting LOC100041343 if it is a PKC substrate. | ||||||
PIK-75, hydrochloride | 372196-77-5 | sc-296089 sc-296089A | 1 mg 5 mg | $28.00 $122.00 | ||
Inhibits p110α isoform of PI3K, leading to selective pathway inhibition which can decrease LOC100041343 activity if it is PI3K-regulated. | ||||||
IC261 | 186611-52-9 | sc-3561 | 5 mg | $137.00 | 11 | |
Inhibits casein kinase 1 (CK1), which can alter the phosphorylation status of proteins regulated by CK1, potentially affecting LOC100041343 activity. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $70.00 $198.00 | 18 | |
Inhibits GSK-3β, potentially altering Wnt signaling and downstream protein activity, including that of LOC100041343 if it is within the Wnt pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, affecting proteins regulated by stress responses and apoptotic pathways, which can influence LOC100041343 activity if it's JNK-related. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
Inhibits FGFR1, which can lead to decreased activity of downstream signaling proteins, potentially affecting LOC100041343 if it is regulated by this pathway. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Inhibits cyclin-dependent kinases (CDKs), which can affect cell cycle progression and proteins associated with CDK regulation, potentially impacting LOC100041343. | ||||||